JNTUK B.Pharm 1-1 2020 Feb Previous Question Paper
Sub. Code: 3827
(OCTOBER 2020 EXAM SESSION)
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PHARM. ‘D’ (POST BACCALAUREATE) DEGREE EXAMINATION
FIFTH YEAR (2009-2010 Regulation)
PAPER III - CLINICAL PHARMACOKINETICS AND PHARMACOTHERAPEUTIC DRUG MONITORING
O.P. Code : 383827
Time : Three hours Maximum : 70 Marks
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- Elaborate on: (4 x 10 =40)
- Explain about Pharmacokinetic / Pharmacodynamic correlation in Drug therapy.
- Describe about adaptive method in population pharmacokinetics.
- Drug dosing in Pediatrics and Elderly patients.
- Explain about the genetic polymorphism in drug metabolism of CYP-450 enzymes.
- Write notes on: (6x5=30)
- Adverse reactions attributed to Genetic difference
- Describe the measurement of Creatinine clearance.
- Pharmacokinetic drug interactions
- General approach for dosage -adjustment in renal disease
- TDM of seizure drugs
- How is dosing interval determined on the basis of therapeutic index of the Drug?
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