Download PTU B.Tech 2021 Jan BT-Biotechnology 5th Sem 78237 Bioinformatics Question Paper

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Roll No. [ ] [ ] [ ] [ ] Total No. of Pages : 02
Total No. of Questions : 18

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B.Tech (BT) (Sem.-5)
BIOINFORMATICS
Subject Code : BTBT-503-18
M.Code : 78237
Time : 3 Hrs. Max. Marks : 60

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INSTRUCTION TO CANDIDATES :

1. SECTION-A is COMPULSORY consisting of TEN questions carrying TWO marks each.
2. SECTION-B contains FIVE questions carrying FIVE marks each and students have to attempt any FOUR questions.
3. SECTION-C contains THREE questions carrying TEN marks each and students have to attempt any TWO questions.

SECTION-A

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Answer briefly :

1. What is flat file format?
2. What are secondary databases?
3. Give brief account on GenBank.
4. What is Global Alignment?

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5. What is CATH?
6. What is E-Value?
7. Name any two MSA tools.
8. What is FASTA?
9. Give significance of Phylogenetic analysis.

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10. Define Block based alignment.

SECTION-B

11. Differentiate between primary and secondary databases.
12. What is the difference between local and global alignment?
13. Explain Dot matrix method.

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14. What is Needleman-Wunsch algorithm?
15. Explain clustering based methods of phylogenetic tree construction.

SECTION-C

16. Explain different types of substitution matrices.
17. Explain Blast word algorithm in detail.

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18. What is phylogenetic analysis? Explain various tree terminologies.

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