This download link is referred from the post: PTU B.Tech 7th Semester Last 10 Years Previous Question Papers|| Punjab Technical University 2011-2021
Roll No.
Total No. of Questions: 18
Total No. of Pages : 02
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B.Tech. (BT) (2012 to 2017) (Sem.-7)
GENOMICS AND PROTEOMICS
Subject Code : BTBT-703
M.Code: 71845
Time: 3 Hrs.
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Max. Marks : 60
INSTRUCTIONS TO CANDIDATES :
- SECTION-A is COMPULSORY consisting of TEN questions carrying TWO marks each.
- SECTION-B contains FIVE questions carrying FIVE marks each and students have to attempt any FOUR questions.
- SECTION-C contains THREE questions carrying TEN marks each and students have to attempt any TWO questions.
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SECTION-A
Write briefly :
- Explain HAPPY mapping.
- Differentiate between bacterial and viral.
- List out the applications of Human Genome project.
- Define Proteome?
- What are protein arrays and its uses?
- What are the applications of structural proteomics?
- What are Orthologs? How are they different from paralogs?
- Explain how is proteomics useful in understanding functions of different proteins?
- Explain RAPD along with its advantages and limitations.
- What is exon shuffling?
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SECTION-B
- Explain the principle of the shot gun approach method for the genome sequencing.
- Describe the serial analysis of gene expression (SAGE) for transcriptome analysis. How is it different from microarray based approach?
- What is the application of transcriptional profiling using transcriptomic analysis?
- What is 2D gel electrophoresis? Write a note on its application in proteomics.
- Define EST and write how it is different from STS? Why is it desirable to select EST from 3'UTR region of genes?
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SECTION-C
- Explain how can X-ray crystallography determine the three dimensional structure of protein?
- What is the importance of metagenomic analysis of microbial communities?
- Write short notes on the following :
- Multiple Sequence alignment
- Proteomic databases
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NOTE: Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.
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This download link is referred from the post: PTU B.Tech 7th Semester Last 10 Years Previous Question Papers|| Punjab Technical University 2011-2021
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