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Roll No. Total No. of Pages : 02
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Total No. of Questions : 18B.Tech. (CSE) (Sem.-5)
COMPUTATIONAL BIOLOGY
Subject Code : BTCS 521-18
M.Code : 78327
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Time : 3 Hrs. Max. Marks : 60INSTRUCTIONS TO CANDIDATES :
- SECTION-A is COMPULSORY consisting of TEN questions carrying TWO marks each.
- SECTION-B contains FIVE questions carrying FIVE marks each and students have to attempt any FOUR questions.
- SECTION-C contains THREE questions carrying TEN marks each and students have to attempt any TWO questions.
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SECTION-A
Write briefly :
- Difference between aerobic and anaerobic respiration:
- What are sense and anti-sense codons?
- What do you mean by TTEMBL and PROSITE?
- Explain Viterbi algorithms for sequence analysis.
- Energetics of krebs cycle.
- Classify proteins.
- Basic principle of hidden markov models.
- Enlist the enzymes used in DNA replication and RNA splicing.
- Discuss the significance of protein structure database.
- Draw a well labelled diagram and functions of DNA.
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SECTION-B
- Briefly discuss DNA transcription and translation process.
- What are the different DNA sequencing techniques?
- Explain the principle and applications of hidden markov models.
- Briefly discuss the techniques for RNA splicing and RNA editing.
- Explain in detail about cell structure and also describe its functions.
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SECTION-C
- Explain the biological significance of glycolysis. Discuss the krebs cycle in detail.
- Describe the different techniques used in gene mapping. Briefly discuss about DNA restriction enzymes.
- Discuss the principles and applications of various protein sequence databases.
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NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.
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