II-MBBS
01221A3+01221A4
Second M.B.B.S. (Supp) Exam. (New
Scheme)
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May-2025PATHOLOGY
Paper- II
Time: Three Hours
Maximum Marks: 100
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Attempt all questions in both sections(Use separate answer book for each
section)
Section-A
Fill in the blanks.
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1. Call-exner bodies seen in type of ovariantumor.
2. is most frequent common cause of
nephrotic syndrome in children.
3. In acute myocardial infarct, area of
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necrosis is histochemicallydemonstrated by lack of stain of stain.
4. Wilson disease is resulting in impaired
excretion into bile.
5. is a clinical syndrome of progressive
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respiratory insufficiency caused bydiffuse alveolar damage.
6. Orphan Annie eye nuclei is a
characteristic of of thyroid.
Answer the following (Multiple choice
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questions)1. Which of the following is a characteristic
feature of Alzheimer's disease?
a. Amyloid plaques
b. Neurofibrillary tangles
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c. Synaptic lossd. Cerebral edema
2. Which of the following is a characteristic
feature of multiple sclerosis?
a. Demyelination
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b. Axonal damagec. Inflammation
d. Gliosis
3. Which of the following is a characteristic
feature of Graves' disease?
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a. Hyperthyroidismb. Hypothyroidism
c. Thyroid nodules
d. Thyroiditis
4. All of the following are histological
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lesions associated with ulcerative colitis,except
a. granuloma
b. inflammatory process limited to
mucosa and superficial mucosa
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c. pseudopolypsd. toxic megacolon
5. 32 year old male patient presented with
history of abdominal pair and blood
mixed stool He gave history of 10 kg
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weight loss from the time of onset ofsymptoms.
Chest X-ray examination was normal
with no lymphadenopathy. On
sigmoidoscopic examination superficial
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ulceration with multiple small polypoidalstructures was noted in the rectum and
sigmoid colon. The involvement was
continuous without intervening normal
area. (UC)+(CRI)
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What is the most probable clinical
diagnosis? Justify.
6. Labelled diagram of morphologic and
molecular changes in adenoma-
Carcinoma sequence.
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3. Mention and write briefly the pathways ofcolorectal carcinoma development.
Write, short note on (any five)
1. Diabetic nephropathy
2. Krukenberg's tumor
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3. Lung abscess4. Risk factors of atherosclerosis
5. Wilm's tumor
6. Seminoma
Explain briefly (Any three)
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1. Pathogenesis of malignantnephrosclerosis
2. Morphology of gallstones
3. Difference between crohn's disease and
ulcerative colitis
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4. Diagnostic criteria for infectiveendocarditis
Section-B
A postmenopausal female presented with
vaginal bleeding. In the ultrasound, the
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endometrium was markedly thickenedwhen compared to normal Curettage was
done and patient was advised
hysterectomy.
1. Write the probable diagnosis.
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2. Describe etiopathogenesis of thedisease.
3. Write its types & histomorphological
features in detail
Write short Note on (Any five)
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1. Fibroadenoma breast2. Dermoid cyst ovary
3. Stages of lobar pneumonia
4. Difference between nephritic and
nephrotic syndrome.
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5. Difference between Tubercular andpyogenic meningitis.
6. Risk factors for carcinoma cervix
Explain briefly (Any four)
1. serous ovarian tumours and mucinous
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ovarian tumours2. Duodenal ulcer and gastric ulcer
3. Lobar pneumonia and lobular
pneumonia.
4. Typel DM and Type2DM
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5. Nephritic syndrome and nephroticsyndrome
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