II-MBBS
01231A3+01231A4
Second M.B.B.S. (Supp) Exam. (New Scheme)
May-2025
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MICROBIOLOGYPaper- II
Time: Three Hours Maximum Marks: 100
Attempt all questions in both sections
(Use separate answer book for each section)
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Section-AQ.1 Fill in the blanks 6x1=6
a. The other name for HBsAg is
b. Alveolar hydatid cyst is caused by
c. CAMP Test is used to identify GBS
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d. Anthrax of the skin is also known ase. A complication of Measles involving CNS is
f. Disease caused by Malassezia furfur is known as
Q.2 Multiple Choice Questions (MCQs) 4x1=4
a. The most common viruses that cause
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meningoencephalitis in children arei. Arboviruses
ii. Herpesviruses
iii. JE Virus
iv. Enterovirus
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b. Oocysts of Toxoplasma gondii are excreted in thefaeces of
i. Cat
ii. Cattle
iii. Sheep
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iv. Humansc. The most effective way of preventing Tetanus is
i. Hyperbaric oxygen
ii. Antibiotics
iii. Surgical debridement & Toilet
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iv. Tetanus Toxoidd. All are true about CSF collection & transport for
diagnosis of pyogenic meningitis except
i. CSF should be collected by lumbar puncture
under strict aseptic & antiseptic conditions
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ii. CSF is divided and sent for cell count,biochemical analysis & bacteriological
examination
iii. CSF being the most precious sample should be
examined immediately
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iv. If there is delay in processing, CSF should berefrigerated
Q.3 26 years female, presented with high grade
fever & burning micturition since 3 days, AUTI 15
a. How the urine sample shall be collected for
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laboratory investigations?b. Which are the common aetiological agents
suspected here & which culture media to be
inoculated for isolation of suspected bacteria?
c. What is significant bacteriuria & how it's
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evaluated?Q.4 Write short notes on (Any five) 5x2=10
a. Discuss pathogenesis & laboratory diagnosis of
Hydatid cyst.
b. Enlist organism causing non-gonococcal
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urethritis.c. Describe morphology, lifecycle & pathogenesis of
round worm
d. Discuss aetiology, risk factors & Laboratory
diagnosis of mucromycosis
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e. Differences between Actinomyces & nocardiaf. Clinical types of plague
Q.5 Explain briefly (Any three) 3x5=15
a. Why pneumococcal polysaccharide vaccines are
not effective under 2 years of age
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b. Why media are heated for three consecutive daysduring Inspissation
c. Why group A streptococci are known as "flesh
eating bacteria"?
d. Why Cowan I strain of staphylococcus is best
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suited for Coagglutination test?Section-B
Q.6 Structured Essay type question with clinical
interpretation 20 Enumerate Hepatitis viruses.
Describe morphology and antigens of Hepatitis B
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virus infection. Discuss various serological markersof Hepatitis B virus in various stages of its
infection. Discuss active and passive immunization
against Hepatitis B virus infection.
Q.7 Write a short notes on (Any five) 5x2-10
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a. Satellitismb. Primary Atypical Pneumonia
c. Bioterrorism
d. Opportunistic mycoses of skin and soft tissues
e. Laboratory diagnosis of gonorrhoea
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f. Standard tests for syphilisQ.8 Explain briefly 4x5=20
a. GenXpert for tuberculosis diagnosis
b. Toxoplasma Avidity Test
c. Tzank smear
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d. Immunoprophylaxis of Rabies***