Rajiv Gandhi University of Health Sciences, Karnataka
III Year Pharm-D Degree Examination - 13-Jan-2020
Time: Three Hours
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Max. Marks: 70 Marks
Pharmaceutical Formulations (RS & RS2)
Q.P. CODE: 2866
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
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LONG ESSAYS (answer any two) 2 x 10 = 20 Marks
- Describe, with examples, the excipients used in the manufacturing of tablets giving their functions.
- Describe in detail the production facilities required to be maintained for parenterals.
- Classify injections as per USP. Describe parenteral suspensions and parenteral emulsions.
SHORT ESSAYS (answer any six) 6 x 5 = 30 Marks
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- Enumerate the film defects. Give the reasons and solutions for the same.
- Explain the extraction of gelatin from different sources.
- Explain the methods of manufacture of soft gelatin capsules.
- Explain the requirements of ophthalmic preparations.
- Explain the methods of filling of liquid orals in the industry.
- Explain the components of reservoir type transdermal drug delivery system.
- Discuss the tablet compression cycle by multistation rotary press.
- Explain the evaluation of emulsions.
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SHORT ANSWERS 10 x 2 = 20 Marks
- Give two examples each for non-sterile semisolids and sterile ophthalmic formulations.
- How is the lower punch responsible for the problem of double impression?
- Enumerate the sizes of hard gelatin capsules in the ascending order of their fill weight.
- List two sources of pyrogens. Suggest two methods of eliminating the pyrogens.
- Enumerate the glass containers used to supply parenterals. Suggest corresponding tests to determine their chemical resistance.
- Explain the syneresis of gel systems.
- Name the instrument/technique used to test any two physical changes in the liquid orals.
- Compared to oral route, decreased dose of the drug is possible through buccal formulations. Justify.
- How is rectal route advantageous to deliver the drugs?
- Enlist the properties of polymers used in implants.
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