Download RGUHS M.Pharm 1st Year 2020 9338 Bio Pharmaceutics And Pharmacokinetics Revised Scheme 4 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharm (Master of Pharmacy) 1st Year (First Semester) 2020 9338 Bio Pharmaceutics And Pharmacokinetics Revised Scheme 4 Previous Question Paper

Rajiv Gandhi University of Health Sciences, Karnataka
First Year M. Pharm Degree Examination - 14-Jan-2020

Time: Three Hours






Max. Marks: 100 Marks

BIO-PHARMACEUTICS AND PHARMACOKINETICS
(Revised Scheme 4)
Q.P. CODE: 9338
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary. Answer any ten questions.

LONG ESSAY (Answer any TEN)
10 X 10 = 100 Marks
1.
Discuss in detail the drug related factors affecting absorption of drugs.
2.
Define Bioavailability and Bioequivalence. Explain the methods to estimate
bioavailability.
3.
Describe In-Vitro methods for the evaluation of drug absorption.
4.
Explain the theories proposed for the dissolution process with labeled diagram.
5.
Classify compartment models. Explain them with concept and schematic
representation.
6.
Explain one compartment model with respect to extra vascular administration.
7.
Describe Mixed order kinetics.
8.
Define protein binding. Explain its kinetics and significance in detail.
9.
Define AUC. Explain the various methods of determining AUC.
10. Explain the terms biotransformation and detoxification. What are the applications of
biotransformation? Describe the metabolism of drugs by conjugation reactions.
11. Explain the mechanism involved in the renal excretion of drugs with suitable examples.
12. Define multiple dosage regimen. Write the advantages and disadvantages of Multiple
dosage regimen. Explain the concept of loading dose in multiple oral dosing.
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