PAPER CODE: MB2019102
KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA STATE - 506002
FIRST MBBS DEGREE EXAMINATIONS: MARCH, 2022
BIOCHEMISTRY (NEW REGULATION) PAPER-II
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Time: 3 Hours Max Marks: 100
Note: Answer all questions.
Give Diagrammatic representation wherever necessary.
Write Long Answer on the following Questions: 2 X15 = 30
- Explain the process of Translation in Eucaryotes under following.
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a) Activation of amino acid,
b) Initiation
c) Elongation.
d) Termination
e) Post translational Modifications, (3+3+3+3+3) - Discuss the IRON metabolism under the following.
a) Food sources.
b) Daily requirement.
c) Functions
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e) Clinical abnormalities. (3+3+3+3+3)
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Write Short Answer on the following Questions: 8X5=40
- Heme synthesis.
- Purine salvage pathway.
- Polymerase chain reaction
- Transamination and its significance.
- Polyamines.
- Jaundice.
- Urea cycle.
- Tumour markers.
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Write Very Short Answer on the following Questions: 10X3=30
- Apoptosis.
- Deficiency manifestations of Vitamin "D".
- Clearance tests.
- Write any three inhibitors of De Novo purine synthesis.
- S-Adenosyl methionine.
- Lesch-Nyhan syndrome and Orotic aciduria.
- Write any three functions of ZINC.
- Functions of Albumin.
- Mention the biochemical defect in
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a) Homocystinuria.
b) Phenylketonuria.
c) Maple syrup urine disease - Functions of Vitamin "C".
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