Download MBBS 1st Year KNRUHS Biochemistry Paper II 2022 March Question Paper

Time: 3 Hours                                                            Max Marks: 100

Note: Answer all questions.

Give Diagrammatic representation wherever necessary.

Write Long Answer on the following Questions:                                                                                  2 X15 = 30

1. Explain the process of Translation in Eucaryotes under following.
   

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   a) Activation of amino acid,
   b) Initiation
   c) Elongation.
   d) Termination
   e) Post translational Modifications,                                                                                  (3+3+3+3+3)

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2. Discuss the IRON metabolism under the following.
   a) Food sources.
   b) Daily requirement.
   c) Functions
   d) Absorption and transport.
   

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   e) Clinical abnormalities.                                                                                                        (3+3+3+3+3)

Write Short Answer on the following Questions:                                                                                  8X5=40

3. Heme synthesis.
4. Purine salvage pathway.
5. Polymerase chain reaction

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6. Transamination and its significance.
7. Polyamines.
8. Jaundice.
9. Urea cycle.
10. Tumour markers.

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Write Very Short Answer on the following Questions:                                                                                  10X3=30

11. Apoptosis.
12. Deficiency manifestations of Vitamin "D".
13. Clearance tests.
14. Write any three inhibitors of De Novo purine synthesis.

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15. S-Adenosyl methionine.
16. Lesch-Nyhan syndrome and Orotic aciduria.
17. Write any three functions of ZINC.
18. Functions of Albumin.
19. Mention the biochemical defect in
    

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    a) Homocystinuria.
    b) Phenylketonuria.
    c) Maple syrup urine disease
20. Functions of Vitamin "C".

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