FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2015
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BIOCHEMISTRY
PAPER - IV
BIO/D/15/03/IV
Time : 3 hours
Max. Marks : 100
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Important instructions:
- Attempt all questions in order.
- Each question carries 10 marks.
- Read the question carefully and answer to the point neatly and legibly.
- Do not leave any blank pages between two answers.
- Indicate the question number correctly for the answer in the margin space.
- Answer all the parts of a single question together.
- Start the answer to a question on a fresh page or leave adequate space between two answers.
- Draw table/diagrams/flowcharts wherever appropriate.
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Write short notes on:
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- What is chromatography? Give principles of adsorption and partition chromatography. 2+(4+4)
- What are the markers of bone turnover? Add a note on their clinical significance. 5+5
- a) What are life style diseases? b) How can they be managed? c) Write the molecular mechanisms by which obesity predisposes a person to coronary heart disease. 2+4+4
- What are stem cells? Add a note on their therapeutic potential and its controversies. 2+(4+4)
- Write the properties and biological effects of dietary fibres in health and disease. Write the mechanism of digestion and absorption of dietary lipids in intestine. 5+5
- State the principle of RT (Reverse Transcriptase)-PCR. Write its application in research and diagnosis giving suitable examples. 4+6
- a) What is the biochemical basis for the action of oral contraceptives? 5+5 b) State the advantages and disadvantages of DNA vaccination.
- Justify that heart is an endocrine organ and its clinical significance. 5+5
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POSSESSION / USE OF CELL PHONES IS NOT PERMITTED INSIDE THE LABORATORY.
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