Download DNB 2015 Dec PATHOLOGY I Question Paper

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FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2015

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Time : 3 hours
Max. Marks : 100

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Important instructions:

1. Attempt all questions in order.
2. Each question carries 10 marks.
3. Read the question carefully and answer to the point neatly and legibly.
4. Do not leave any blank pages between two answers.

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5. Indicate the question number correctly for the answer in the margin space.
6. Answer all the parts of a single question together.
7. Start the answer to a question on a fresh page or leave adequate space between two answers.
8. Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

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1. Statistical analysis in research methodology. (5)
2. Signal transduction pathways. (5)

1. Mechanisms of hypertrophy. (4)
2. Mechanism of dystrophic calcification. (3)
3. Ochronosis. (3)

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1. a) Mechanism and effects of leukocyte activation. (5)
   b) Abnormalities in tissue repair. (5)

1. a) Pathogenesis of thrombus formation and its progression. (6)
   b) Morphological features observed in irreversible shock. (4)

1. a) Angioedema. (3)
   

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   b) Principles and effects of gene mutations. (3)
   c) Mechanism of hypercholesterolemia and its consequences. (4)

1. a) Role of NK cells in immune system. (3)
   b) Mediators of immediate hypersensitivity. (3)
   c) Mechanisms of SLE. (4)

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1. a) Indications for and complications of transplantation of hematopoietic stem cells. (5)
   b) Role of epigenetic changes in carcinogenesis. (5)

1. a) Pathological features of lead poisoning. (5)
   b) Systemic effects of protein energy malnutrition. (5)

1. a) Pathophysiology and lab diagnosis of phenylketonuria. (5)
   

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   b) Mechanism of apoptosis. (5)

1. a) Pathological feature of cryptococcal infection and its lab diagnosis. (5)
   b) Pathogenesis of atheromatous plaque formation. (5)