FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2015
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MEDICAL ONCOLOGY
PAPER - II
MED.ONCO/D/15/17/II
Time : 3 hours
Max. Marks : 100
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Important instructions:
- Attempt all questions in order.
- Each question carries 10 marks.
- Read the question carefully and answer to the point neatly and legibly.
- Do not leave any blank pages between two answers.
- Indicate the question number correctly for the answer in the margin space.
- Answer all the parts of a single question together.
- Draw table/diagrams/flowcharts wherever appropriate.
- Start the answer to a question on a fresh page or leave adequate space between two answers.
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Write short notes on:
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- a) A 26 year old lady was diagnosed with stage IIBx Hodgkin’s Lymphoma. Explain briefly the treatment options, prognosis for initial treatment and after relapse. (3+3)+4
- a) Enumerate the primary tumors of testes in a 25 years old male.
- b) Outline the treatment of high risk mixed germ cell tumor and its long term complications.
- a) Importance of taking family history in breast cancer.
- b) Various interventional strategies evolved thereof in the management of a 35 year old lady with stage III breast cancer with strong family history.
- a) How knowledge of molecular biology of Glioblastoma multiforme has impacted its management?
- b) Epidemiology of esophageal cancer.
- a) Outline the combined modality treatment for a locally advanced esophageal cancer in a 55 year old lady with ECOG Performance Score of 1.
- b) Classify anti fungal drugs.
- a) Indications, merits and demerits of each class of anti fungal agents.
- b) Risk factors for Gall-bladder and Pancreas cancer.
- a) Role of adjuvant treatment in adenocarcinoma of pancreas and gall bladder.
- b) Merits and demerits of various conditioning regimen used for allogenic hemopoietic stem cell transplantation of acute myeloblastic leukemia (AML).
- a) Name potential regimen related complications in 1-30 days of transplant.
- b) Classify hormonal agents used for treatment of prostate cancer. Briefly mention their indications, pharmacology and mechanism of resistance and strategies to overcome resistance.
- a) TNM staging of urinary bladder cancer.
- b) Compare various treatment options in a 50 year old male with T1N0 urinary bladder cancer.
- Classification and pathology malignant brain tumors.
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