DNB 2013 June Previous Question Papers-(Diplomate of National Board) Under NBE
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FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
JUNE 2013
PATHOLOGY
PAPER - II
PATHO/J/13/32/II
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Time : 3 hours
Max. Marks : 100
Attempt all questions in order.
Each question carries 10 marks.
- Define and classify anemia of chronic disease. What is its pathogenesis and management. (5+5)
- Classify immune hemolytic anemia. Discuss the pathogenesis of warm and cold antibody type autoimmune hemolytic anemias. Discuss in brief Immunologic tolerance. (1+4+5)
- Enlist various diseases under the category of chronic lympho-proliferative disorders. Give the role of flow-cytometry with the panel of markers required for diagnosis and detection of residual disease. (4+6)
- Discuss the principle behind the working of semi automated, fully automated and five part differential blood cell counters. (3+3+4)
- Describe and classify functional disorders of leukocytes. What are their clinico-pathologic features and diagnostic modalities? (5+5)
- Describe the diagnostic criteria for multiple myeloma and MGUS. What is monoclonal gammopathy of renal significance? (8+2)
- Give the diagnostic algorithm in a patient of bleeding disorder. What are the various qualitative platelet defects and how are they diagnosed? (6+4)
- Give the WHO classification of myeloproliferative neoplasms. Which are the molecular markers used for diagnosis of these disorders. Give the pathogenesis and morphology of primary myelofibrosis. (1+3+6)
- What is the role of nucleic acid testing (NAT) laboratory in Transfusion Medicine? Discuss in brief Hemolytic Transfusion Reactions. (5+5)
- How will you diagnose a case of acute myelomonocytic leukemia? Discuss the prognostic factors of acute lymphoblastic leukemia. (5+5)
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POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.
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