Download B.Pharm 1st Year 2015 August 564252 Pharmaceutical Organic Chemistry Question Paper

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B.PHARM. DEGREE EXAMINATION

FIRST YEAR

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PAPER II - PHARMACEUTICAL ORGANIC CHEMISTRY

Q.P. Code: 564252

Time : Three Hours Maximum : 100 marks

Answer ALL questions

1. Essay: (2x20=40)
   1. Preparation and reactions of alkenes.

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   2. Explain the mechanism, reactivity and orientation of E1 & E2 reaction.
2. Short notes : (8 x5=40)
   1. Describe Coulson and Moffitt’s modification.
   2. Mention the methods of preparation and reactions of Ketones.
   3. Give the preparation, properties of Diphenyl methane.

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   4. Write the preparation, tests for purity and medicinal uses of Dicophane and Gammaxene.
   5. Explain the Aromaticity character of Benzene.
   6. Write the preparation and synthetic utility of Aceto -Acetic ester.
   7. Write the preparation and properties of Anthracene.
   8. Explain the mechanism of Diel’s - Alder reaction.

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3. Short answers: (10x 2=20)
   1. Define Dipole moment.
   2. Write about Huckel’s rule.
   3. Define Mesomeric effect.
   4. Give the structural formula of Beta-naphthol and Cyclohexane.

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   5. Give the test for purity of Amphetamine.
   6. Brief about oxidation of primary alcohols.
   7. Define Tautomerism.
   8. Write any one preparation of Benzene.
   9. Write the stability of carbocations.

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   10. Enumerate the functional derivatives of carboxylic acid.

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