B.PHARMACY DEGREE COURSE (NON-SEMESTER EXAMINATIONS)
FIRST YEAR (Regulation 2009-2010)
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PAPER II - PHARMACEUTICAL ORGANIC CHEMISTRYQ.P. Code: 564252
Time: Three hours Answer ALL questions Maximum: 100 Marks
- I. Elaborate on: (2x20=40)
- Write down the general methods of preparation of Alkyl and Aryl halides.
- Explain the methods of preparation and synthetic utility of Malonic ester.
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- Describe the mechanism, kinetics, stereochemistry and relative reactivity of alkyl halides in SN1, SN2 reactions.
- II. Write notes on: (8 x5=40)
- Write the methods of preparation of Amines.
- Write a detailed note on FREE radicals.
- Explain the preparation and synthetic utility of Diazonium salt.
- Write the methods of preparation of Alkanes.
- Describe Williamson synthesis.
- Mention the methods of preparation and reactions of Ketone.
- Write the preparation and synthetic utility of Grignard reagent.
- Give the preparation and medicinal uses of amphetamine.
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- III. Short answers on: (10x2=20)
- Methyl salicylate.
- Hoffmann degradation of amines.
- Explain bond fission.
- Aromaticity of Benzene.
- Citric acid.
- Anthracene.
- Give the structure of phenol and aniline.
- Brief about oxidation of Aldehyde.
- Carbanion.
- Oxidation of primary alcohol.
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