SECOND YEAR B.PHARM. EXAM
Sub. Code: 4256
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Paper I - PHYSICAL PHARMACEUTICS
Time : Three hours (180 Min) Maximum: 100 Marks
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I. Elaborate on: (2 x 20 = 40 marks)
- Describe about the different methods of analysis of complexes with examples.
- Discuss about the preparation and evaluation of pharmaceutical suspensions.
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II. Write notes on: (8 x 5 = 40 marks)
- Explain the principles of gastro intestinal absorption of drugs.
- What is buffer capacity? How do you determine the buffer capacity?
- Describe the derived properties of powders.
- Write the applications of rheology in pharmacy.
- Explain the factors influencing rate of reaction.
- Write notes on spreading coefficient.
- Discuss about instabilities of emulsion.
- Describe the optical properties of colloids.
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III. Short Answers: (10 x 2 = 20 marks)
- Half life.
- Thixotropy.
- Protein binding of drugs.
- Applications of colloidal system.
- Solubilization.
- Hydrophilic lipophilic balance.
- Viscosity.
- Multiple emulsions.
- Protective colloids.
- Examples of pharmaceutical buffers.
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