Download B.Pharm 2nd Year 2014 February 564258 Advanced Pharmaceutical Organic Chemistry Question Paper

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(LE 4258) FEBRUARY 2014 Sub. Code: 4258

SECOND YEAR B.PHARM. EXAM

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PAPER III - ADVANCED PHARMACEUTICAL ORGANIC CHEMISTRY

Q.P. Code: 564258

Time: Three Hours Maximum: 100 marks

1. I. Elaborate on: (2X20=40)
   1. Describe the absolute and relative configuration.
   2. Stereospecific and stereoselective synthesis.

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2. Explain the chemistry and constitution of citral.

3. II. Write notes on: (8X5=40)
   1. Clemmenson’s reduction.
   2. Reaction of furan.
   3. Stereochemistry of cyclic compounds.

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   4. Chemistry of papaverine.
   5. Relationship between menthol and thymol.
   6. Schmidt rearrangement.
   7. Synthesis of thiophene.
   8. Structure and uses of Vitamin B and E.

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4. III. Short Answers on: (10X2=20)
   1. Define glycoside.
   2. Classify terpenoids.
   3. Structure and uses of digoxin.
   4. Define plane of symmetry.

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   5. Fischer projection.
   6. Structure of hesperidin.
   7. Two reactions of pyridine.
   8. Structure of atropine and ephedrine.
   9. Darzen’s reaction.

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   10. Two synthesis of pyrimidine.

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