Download B.Pharm 2nd Year 2015 August 564256 Physical Pharmaceutics Question Paper

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[LH 4256]

AUGUST 2015 Sub. Code: 4256

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B.PHARM. DEGREE EXAMINATION

SECOND YEAR

PAPER I - PHYSICAL PHARMACEUTICS

Time : Three Hours

Q.P. Code: 564256

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Maximum : 100 marks

Answer All Questions

1. Essay: (2 x 20 = 40)
   1. Define diffusion. Describe steady state of diffusion. Explain the factors affecting dissolution.
   2. What is buffer capacity? Explain the various methods for adjusting tonicity. Explain the importance of pharmaceutical buffers.

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2. Short notes : (8 x 5 = 40)
   1. Protein binding of drugs.
   2. Theory of emulsification.
   3. Nernst and zeta potential.
   4. Newtonian systems.
   5. Clathrates.

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   6. Spreading coefficient.
   7. Determination of order of reaction.
   8. Particle size and size distribution.
3. Short answers: (10 x 2 = 20)
   1. Define osmosis

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   2. Brownian motion.
   3. Multiple emulsion.
   4. HLB values.
   5. Noyes whitney equation.
   6. Porosity.

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   7. Kinematic viscosity.
   8. Rheopexy.
   9. Chelates.
   10. Specific rate constant.

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