B.Pharm 2nd Year Last 12 Years 2010-2022 Previous Question Papers (Bachelor of Pharmacy)
[LB 4258] AUGUST 2012 Sub. Code: 4258
SECOND YEAR B.PHARM. EXAM
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Paper 111 - ADVANCED PHARMACEUTICAL ORGANIC CHEMISTRY
Q.P. Code : 564258
Time: Three hours Maximum: 100 Marks
(180 Min) Answer ALL questions in the same order
I. Elaborate on: Pages Time Marks
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(Max.)(Max.)(Max.)- Define and classify alkaloids with examples. Discuss the chemistry and pharmacological activity of ephedrine. 19 33 20
- Write the definition, reaction, mechanism and applications of (1)Beckmann rearrangement and (i1) Birch reduction. 19 33 20
II. Write notes on:
- Write a brief note on Absolute configuration. 3 8 5
- Explain Clemmenson’s reduction in detail. 3 8 5
- (1)Fischer indole synthesis (i1) Skraup synthesis. 3 8 5
- Explain the oxidative uses of lead tetraacetate. 3 8 5
- Give any two methods of preparation of Oxazole and Thiophene. 3 8 5
- Explain conformational analysis of ethane. 3 8 5
- Write short notes on Atropine and related alkaloids. 3 8 5
- Write the electrophilic substitution reactions of Pyrrole. 3 8 5
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III. Short Answers:
- Define racemic modification.
- What are enantiomers.
- Write the definition and reaction for Meerwein Pondroff reduction. 1 5 2
- Give any two methods of preparation of pyrimidine. 1 5 2
- What is dehydrogenation. 1 5 2
- What are flavonoids. 1 5 2
- Write any two uses of Selenium oxide. 1 5 2
- Define alkaloids and give examples. 1 5 2
- Write the structure of 1)Vitamin D 11)Ephedrine 1 5 2
- Give any two reactions of thiophene. 1 5 2
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