Download B.Pharmacy (Bachelor of Pharmacy) 2nd Year (Second Year) 2012 August 564258 Advanced Pharmaceutical Organic Chemistry Previous Question Paper
[LB 4258]
AUGUST 2012
Sub. Code: 4258
SECOND YEAR B.PHARM. EXAM
Paper III ? ADVANCED PHARMACEUTICAL ORGANIC CHEMISTRY
Q.P. Code : 564258
Time: Three hours
Maximum: 100 Marks
(180 Min) Answer ALL questions in the same orde
I. Elaborate on:
Pages Time Marks
(Max.)(Max.)(Max.)
1. Define and classify alkaloids with examples.Discuss
the chemistry and pharmacological activity of ephedrine. 19
33
20
2. Write the definition, reaction, mechanism and
applications of (i)Beckmann rearrangement and
(ii) Birch reduction.
19
33
20
II. Write notes on:
1. Write a brief note on Absolute configuration.
3
8
5
2. Explain Clemmenson's reduction in detail.
3
8
5
3. (i)Fischer indole synthesis (ii) Skraup synthesis.
3
8
5
4. Explain the oxidative uses of
lead
tetraacetate.
3 8 5
5. Give any two methods of preparation of Oxazole
and
Thiophene.
3 8 5
6. Explain conformational analysis of ethane.
3
8
5
7. Write short notes on Atropine and related alkaloids.
3
8
5
8. Write the electrophilic substitution reactions of Pyrrole. 3
8
5
III. Short Answers:
1. Define
racemic
modification.
1 5 2
2. What are enantiomers.
1
5
2
3. Write the definition and reaction for Meerwein
Pondroff
reduction.
1 5 2
4. Give any two methods of preparation
of
pyrimidine. 1 5 2
5. What is dehydrogenation.
1
5
2
6. What are flavonoids.
1
5
2
7. Write any two uses of Selenium oxide.
1
5
2
8. Define alkaloids and give examples.
1
5
2
9. Write the structure of i)Vitamin D ii)Ephedrine
1
5
2
10. Give any two reactions of thiophene.
1
5
2
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