Download B.Pharm 2nd Year 2021 September 564258 Advanced Pharmaceutical Organic Chemistry Question Paper

Download B.Pharmacy (Bachelor of Pharmacy) 2nd Year (Second Year) 2021 September 564258 Advanced Pharmaceutical Organic Chemistry Previous Question Paper

[BPHARM 0921] SEPTEMBER 2021 Sub. Code: 4258

(FEBRUARY 2021 EXAM SESSION)



B. PHARMACY DEGREE EXAMINATION

SECOND YEAR ? (NON-SEMESTER)

PAPER III ? ADVANCED PHARMACEUTICAL ORGANIC CHEMISTRY

Q.P. Code: 564258

Time: Three hours



Answer ALL Questions Maximum: 100 Marks

I. Elaborate on:

(2 x 20 = 40)

1. What are Purines? Elucidate the structure of Uric a

between caffeine, theophylline and theobromine.

2. Explain the mechanism and applications of

a) Birch reduction

b) Meerwein Ponndorf reduction.



II. Write notes on:

(8 x 5 = 40)

1. Explain the chemistry of Vitamin E.

2. Give reasons for the following:

a) Explain why the electrophilic substitution reactions of Pyrrole predominantly

occur at 2nd position than 3rd position.

b) Explain why Pyrrole and Furan is more reactive than Thiophene.

3. What is resolution of Racemic modification? Explain the method of resolution by

biochemical separation.

4. Define optical activity. What are the various optical isomers possible in compounds

containing two different chiral carbons?

5. Explain Fischer Indole synthesis.

6. Explain Cahn Ingold and Prelog system for assigning configuration based on

sequence rules.

7. Explain the chemistry and pharmacological actions of Digitoxin.

8.


III. Short answers on:

(10 x 2 = 20)


1. What is Darzen's reaction?

2. Distinguish between Enantiomers and Diasteromers.

3. Why nitrobenzene is mostly used as oxidizing agent in Skraup synthesis.

4. Mention two uses of Lithium aluminum hydride.

5.

6. Give two methods for the synthesis of Imidazole.

7. Write any two reactions of Furan.

8. What is Fischer projection?

9. Explain briefly D and L system of nomenclature.

10. Write the structure and use of Atropine.

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