August 2011
[KZ 4267]
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Sub. Code : 4267
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THIRD B.PHARM. EXAMINATION
Paper I - FORMULATIVE PHARMACY AND BIOPHARMACEUTICS
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Q.P. Code : 564267Time : Three hours
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Maximum: 100 Marks
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Answer ALL questions.
I. LONG ESSAYS
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(2 x 20 = 40)
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1. a) Preparation, evaluation and applications of nanoparticles.
b) Physico chemical factors affecting the bio availability of drugs.
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2. a) Discuss the protocols followed in the preformulation studies.b) Explain the bioequivalence testing procedures.
II. SHORT NOTES
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(8 x 5 = 40)1.Evaluation of microcapsules.
2. Osmotic drug delivery systems.
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3. Protocol followed for the stability testing of pharmaceutical products.
4. Types of machinery employed for compression of tablets.
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5. Compartmental models and its significance.6. Film defects and its rectification.
7. Hard gelatin capsules.
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8. Discuss the different types of prolonged action pharmaceuticals with suitable
examples.
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III. SHORT ANSWERS--- Content provided by FirstRanker.com ---
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(10 x 2 = 20)1. Polymorphism.
2. Biological half life.
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3. Co- acervation and phase separation.
4. Slugging.
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5. Mean kinetic temperature.7. Base absorption.
8. Racemisation.
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9. Chipping and lamination.
10. Grades of gelatin used for the preparation of capsules.
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