2013
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Sub. Code: 4270
FOURTH YEAR B.PHARM. EXAM
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PAPER IV ? MODERN METHODS OF PHARMACEUTICALANALYSIS
Q.P. Code: 564270
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Time: Three Hours
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Maximum: 100 marks
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(180 Min)
I. Elaborate on:
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(2X20=40)--- Content provided by FirstRanker.com ---
1. Derive an expression for beer-lamberts law and write
the general principle, construction working of double
beam UV spectrophotomete
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2. a) Write the principle and applications of countercurrent extraction and gel filtration.
b) Explain the principle and various types of curves
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in conductometric titrations.--- Content provided by FirstRanker.com ---
II. Write notes on:
(8X5=40)
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1. Explain the sample handling techniques in IRspectroscopy.
2. Explain the principle involved in nephlo- turbidimetry.
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3. Write the sampling procedure as per GLP.4. Explain the factors affecting fluorescence intensity.
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5. What are the different detection techniques used in
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paper chromatography.6. What are the Pharmaceutical applications of X-ray
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diffraction?
7. What are the different methods available to induce
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ionization of a sample in mass spectroscopy.8. Explain amperometric titration curves with example.
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III. Short Answers on:(10X2=20)
1. Define the term Retention time.
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2. What is chemical shift in NM
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3. Explain Bathochromic shift.
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4. Photoelectric colorimete
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5. Detectors used in Gas chromatography.6. Give advantages of preparatory HPTLC plates.
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7. Define singlet and triplet states.
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8. Define diffusion current and residual current.
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9. Explain dead stop end point technique.
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10. Write any two factors which influence vibrationalfrequencies.
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