Download B.Pharm 4th Year 2012 August 564267 Formulative Pharmacy And Biopharmaceutics Question Paper

(LB 4267)

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AUGUST 2012

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Sub. Code: 4267

FOURTH YEAR B.PHARM. EXAM

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Paper I ? FORMULATIVE PHARMACY

AND BIOPHARMACEUTICS

Q.P. Code : 564267

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Time: Three Hours

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Maximum: 100 marks

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(180 Min) Answer ALL questions in the same orde

I. Elaborate on:

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Pages Time Marks

(Max.)(Max.)(Max.)

1. Discuss in detail about the physicochemical properties

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that affect the formulation, stability and bioavailability
of drugs in dosage forms.

19

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33

20

2. Explain about the types, Formulation, defects and

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manufacturing of tablets in large scale production.

19

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33

20

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II. Write notes on:

1. Evaluation

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of

tablets.

3 8 5

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2. Hard gelatin capsules.

3

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8

5

3. Micoencapsulation by co ? acervation phase separation. 3

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8

5

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4. Techniques used in design of prolonged action

dosage

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form.

3 8 5

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5. Method of preparation of Liposomes.

3

8

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5

6. Factors affecting the absorption of drug.

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3

8

5

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7. Pharmacokinetic

parameters.

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3 8 5

8. Methods used in coating of tablets.

3

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8

5

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III. Short Answers:

1. Name the enteric coated polymers.

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1

5

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2

2. Microencapsulation.

1 5 2

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3. Soft gelatin capsule.

1

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5

2

4. Define

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Nanoparticles.

1 5 2

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5. Dental

cones.

1 5 2

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6. Implants.

1 5 2

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7. Renal

clearance.

1 5 2

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8. Bioavailability.

1 5 2

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9. Spray

congealing.

1 5 2

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10. Spinhale 1 5 2

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