Download B.Pharmacy (Bachelor of Pharmacy) 4th Year (Final Year) 2014 August 564270 Odern Methods of Pharmaceutical Analysis Previous Question Paper
[LF 4270]
AUGUST 2014
Sub. Code: 4270
FOURTH YEAR B.PHARM. DEGREE EXAMINATION
Paper IV - MODERN METHODS OF PHARMACEUTICAL ANALYSIS
Q. P. Code: 564270
Time: Three Hours
Maximum: 100 Marks
Answer All Questions
I. Essay Questions:
(2 x 20 = 40)
1. a) Write the principle, preparation, procedure and method of detection
in Column chromatography.
b) What is the different carrier gases used in gas chromatography and
what are the ideal requirements of the carrier gas. Also give
the application of gas chromatography.
2. a) Give the principle, theory instrumentation of mass spectrometer and
application of mass spectroscopy.
b) Describe the principle and instrumentation involved in Flame emission
spectroscopy.
II. Short Notes:
(8 x 5 = 40)
1. Describe with neat diagram the working principles of nepheloturbidimete
2. Explain the different types of detection technique used in paper chromatography.
3. Explain the current voltage curve and various currents in polarographic
measurements.
4. Explain amperometric titrations of curves with example.
5. What is principle and procedure for ultra-centrifuge?
6. Explain shielding, de-shielding and spin coupling in NMR spectroscopy.
7. Describe the parameters of analytical method validation.
8. Write on Radioimmunoassay.
III. Short Answers:
(10 x 2 = 20)
1. Define Chromophores and Auxochromes.
2. Explain photoelectric colorimete
3. What is Rf value and retention volume?
4. Explain the term quenching.
5. What is finger print region?
6. Draw the conductometric titration curve for a strong acid vs a mixture of
strong and weak base.
7. Give bragg's equation in x-ray diffraction technique.
8. What are polarographicsupressors?
9. What is function of filter and monochromator?
10. Explain electrochemical cell.
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