(LE 4267)
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FEBRUARY 2014
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Sub. Code: 4267
FOURTH YEAR B.PHARM. EXAM
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PAPER I ? FORMULATIVE PHARMACY AND BIOPHARMACEUTICSQ.P. Code: 564267
Time: Three Hours
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Maximum: 100 marks
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I. Elaborate on:
(2X20=40)
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1. Discuss about the bioavailability and bioequivalence testing.
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2. Discuss about the quality control testing of tablets.II. Write notes on:
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(8X5=40)
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1. Solubility2. Chemical degradation
3. Materials for production of hard gelatin capsules
4. Spray drying ? Spray congealing
5. Defects in tablets manufacturing
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6. Liposome7. Drug elimination
8. Clearance
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III. Short Answers on:
(10X2=20)
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1. Precompression
2. Polymorphism
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3. Wetting4. Size of hard gelatin capsules
5. Enteric coating
6. Apparent volume of distribution
7. Methods of microencapsulation
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8. Hypodermic tablets9. Biopharmaceutics
10. Application of nanoparticles
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