Download B.Pharm 4th Year 2015 August 564267 Formulative Pharmacy And Biopharmaceutics Question Paper

[LH 4267] AUGUST 2015 Sub. Code: 4267

B.PHARM. DEGREE EXAMINATION

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FOURTH YEAR

PAPER I ? FORMULATIVE PHARMACY AND BIOPHARMACEUTICS

Q.P. Code: 564267

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Time : Three Hours

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Maximum : 100 marks

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Answer All Questions

I. Essay:

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(2 x 20 = 40)

1. What are pre-formulation studies? Explain about physiochemical properties of the

drugs that are determined in pre-formulation studies and their importance.

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2. Write a note on objectives of tablet coating. Explain the different types of coating

and evaluation of coated tablets.

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II. Short notes :

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(8 x 5 = 40)

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1. Liposomes.

2. Drug elimination

3. Hard gelatin capsules.

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4. Microencapsulation by co-acervation phase separation.

5. Techniques used in design of prolonged action dosage form.

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6. Write preparation and application of nanoparticles.

7. Factors affecting drug absorption.

8. Invitro - invivo correlation.

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III. Short answers:

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(10 x 2 = 20)

1. Total body clearance.

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2. Composition of soft gelatin capsules.

3. Coating materials in microcapsules.

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4. Define pharmacokinetics.

5. Renal clearance.

6. Spray drying.

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7. Bioequvalency testing.

8. What is bloom strength?

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9. Classification of different types of tablets.

10. Anti-oxidants.

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