(LI 4267)
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FEBRUARY 2016Sub. Code: 4267
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FOURTH YEAR B.PHARM. EXAMINATION
PAPER I ? FORMULATIVE PHARMACY AND BIO-PHARMACEUTICS
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Q.P. Code: 564267
Time: Three hours
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Maximum: 100 Marks
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I. Essay:
(2 x 20 = 40)
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1. Differentiate hard and soft gelatin Capsules. Discuss about the material used in
capsule. Explain the method of manufacturing of soft gelatin capsule by rotary die
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process.2. Write on the different types of Transdermal drug delivery systems and their
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evaluation.II. Short notes:
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(8 x 5 = 40)
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1. Processing problems of tablet dosage form.
2. Write advantages and limitation of Prolonged Action Pharmaceuticals.
3. Spray drying ?Spray congealing.
4. Pan coating.
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5. Apparent volume of distribution and total body clearance.6. Bioequvalency testing.
7. Discuss the application of stability studies.
8. Polymorphism and its influence in the formulation of solid dosage form.
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III. Short answers:
(10 x 2 = 20)
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1. Importance of tablet coating.2. Write microencapsulation techniques.
3. Storage of capsule dosage forms.
4. Write chemical properties of drugs.
5. Organoleptic property.
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6. Classification of liposomes.7. Define Bio-pharmaceutics.
8. Solubility.
9. Slugging.
10. Biological half life.
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