Download B.Pharm 4th Year 2016 February 564270 Modern Methods of Pharmaceutical Analysis Question Paper

Download B.Pharmacy (Bachelor of Pharmacy) 4th Year (Final Year) 2016 February 564270 Modern Methods of Pharmaceutical Analysis Previous Question Paper

(LI 4270)



FEBRUARY 2016



Sub. Code: 4270



FOURTH YEAR B.PHARM. EXAMINATION

PAPER IV ? MODERN METHODS OF PHARMACEUTICAL

ANALYSIS

Q.P. Code: 564270

Time: Three hours









Maximum: 100 Marks



I. Essay:

(2 x 20 = 40)

1. a) Write the principle, instrumentation and applications of UV-Vis
Spectrophotometry.

2. a) Explain the principles and applications of AAS.

b) Explain the working principle and instrumentation of fluorimetry with a neat
labeled diagram.


II. Short notes:

(8 x 5 = 40)

1. Explain the construction and working of Hydrogen electrode.
2. Write a note on ultracentrifugation.
3. Explain briefly the preparation & activation of TLC plates.
4. List the various detectors used in HPLC. Explain in detail the working principle of

UV detector with a neat labeled diagram.

5. Write a note on Electron Spin Resonance spectroscopy.
6. Write short notes on conductometric titrations.
7. Describe the instrumentation of NMR with a neat diagram.
8. Write a note on sample handling in IR spectroscopy.



III. Short answers:

(10 x 2 = 20)

1. What is Retention time and Rf value?
2. Define isocratic & gradient elution.
3. Write any two advantages of Amperometric titrations.
4. Write Nernst equation. What is its significance?
5. Define migration current.
6. Define fluorescence.
7. Define hypso chromic and hyper chromic shift.
8. Write any two applications of Nephelo-turbidimetry.
9. List various types of cation and anion exchangers.
10. Define Base peak.



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