Download B.Pharm 4th Year 2017 August 564267 Formulative Pharmacy And Bio Pharmaceutics Question Paper

(LL 4267)

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AUGUST 2017 Sub. Code: 4267



B.PHARM. DEGREE EXAMINATION

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FOURTH YEAR

PAPER I ? FORMULATIVE PHARMACY AND BIO-PHARMACEUTICS

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Q.P. Code: 564267

Time: Three hours

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Maximum: 100 Marks

I. Elaborate on: (2 x 20 = 40)

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1. Define Absorption. Explain the physico chemical factors affecting Drug

Absorption.

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2. Write in detail the method of preparation of Liposomes and its applications.

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II. Write notes on:

(8 x 5 = 40)

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1. Influence of Chemical properties of drug in the development of Pharmaceutical

dosage form.

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2. Processing problems of Tablet dosage form.
3. Wurster air suspension technique.
4. Alzet Osmotic pump.
5. Types and components of transdermal patches.
6. Nanoparticles.

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7. Pharmacokinetic parameters.
8. Evaluation of capsules.

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III. Short answers on:

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(10 x 2 = 20)

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1. Objectives of pre-formulation study.
2. Importance of solubility.

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3. Binders and dis-integrants.
4. Double compression.
5. Steps involved in sugar coating.
6. Orange peel effect.
7. Basic components of osmotic system.

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8. Compartment model.
9. Endocytosis.
10. Bioavailability and bioequivalence.

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