Download B.Pharm 4th Year 2019 August 564267 Formulative Pharmacy And Bio Pharmaceutics Question Paper

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(LP 4267)

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AUGUST 2019 Sub. Code: 4267

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B.PHARM. DEGREE EXAMINATION

FOURTH YEAR

PAPER I ? FORMULATIVE PHARMACY AND BIO-PHARMACEUTICS

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Q.P. Code: 564267

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Time: Three hours

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Maximum: 100 Marks

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I. Elaborate on: (2 x 20 = 40)


1. Discuss the pharmaceutical and biological factors that affect absorption of drugs.

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2. Explain about Bio-availability and Bio-equivalency studies.

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II. Write notes on:

(8 x 5 = 40)

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1. Physical factors of drug that affect stability of dosage form.
2. Accelerated stability studies.
3. Processing problems in tablet manufacturing.
4. Film coating of tablets.

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5. Hard gelatin capsule.
6. Benefits and limitation of sustained release preparations.
7. Osmotic drug delivery system.
8. Preparation of microspheres.

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III. Short answers on:

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(10 x 2 = 20)

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1. Dental cone.
2. Excipients for tablet manufacturing.
3. Dry granulation in tablet production.
4. Composition of soft gelatin capsules.
5. Bloom strength.

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6. Benefits of nanoparticles.
7. Enteric coating.
8. Drug elimination.
9. Pharmacokinetic parameters.
10. Compartment models.

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