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(LP
4269)
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AUGUST 2019 Sub. Code: 4269
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B.PHARM. DEGREE EXAMINATION
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FOURTH YEARPAPER III ? PHARMACOLOGY - II
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Q.P. Code: 564269
Time: Three hours
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Maximum: 100 Marks
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I. Elaborate on:(2 x 20 = 40)
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1. Classify beta-lactam antibiotics and describe mechanism of action, therapeutic
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uses and adverse effect of any two beta-lactam antibiotics.2. Classify antineoplastic agents. Discuss the mechanism of action, adverse drug
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reaction, therapeutic uses of alkylating agents and antimetabolites.II. Write notes on:
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(8 x 5 = 40)
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1. Define and classify fibrinolytics. Write the significance of newer heparin
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derivatives.2. Describe the phases involved in clinical trials.
3. Write therapeutic uses and side effects of sulphonamides.
4. Classify antiulcer agents. Describe the H2 receptor blockers.
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5. Write note on anti fungal agents.
6. Explain mechanism of action of fluoroquinolones.
7. Describe various types of poisoning and its treatment.
8. Write note on immunosuppressant.
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III. Short answers on:
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(10 x 2 = 20)
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1. Write the functions of serotonin.2. Give examples for osmotic purgative.
3. Write two uses of prostaglandin agonist.
4. Name the two anti-thyroid drugs.
5. Note on triple response.
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6. Define the term lepra reaction.7. What is the antidote for lead poisoning?
8. Name any two prokinetics.
9. What is ANOVA?
10. Note on therapeutic use of betahistine.
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