Download B.Pharm 4th Year 2019 August 564270 Modern Methods of Pharmaceutical Analysis Question Paper

Download B.Pharmacy (Bachelor of Pharmacy) 4th Year (Final Year) 2019 August 564270 Modern Methods of Pharmaceutical Analysis Previous Question Paper

(LP 4270)



AUGUST 2019 Sub. Code: 4270



B.PHARM. DEGREE EXAMINATION

FOURTH YEAR

PAPER IV ? MODERN METHODS OF PHARMACEUTICAL

ANALYSIS

Q.P. Code: 564270

Time: Three hours









Maximum: 100 Marks



I. Elaborate on:

(2 x 20 = 40)



1. a) Write in detail about the principle and instrumentation of HPLC with a neat

diagram.
b) Write about the various types of curves in conductometric titrations.

2. a) Explain about the principle and instrumentation of fluorimete

b) Explain the factors affecting the fluorescence intensity.


II. Write notes on:

(8 x 5 = 40)



1. Derive an equation for Beer-Lamberts Law.
2. Explain the reaction of amino acid with Ninhydrin reagent in paper

chromatography.

3. Sources used in IR Spectroscopy.
4. What are the types of ion exchange resins used in Ion exchange chromatography?
5. Write a note on the preparation and activation of TLC plates.
6. Short note on coupling constant.
7. Write notes on GLP.
8. Potentiometric titrations.



III. Short answers on:

(10 x 2 = 20)



1. Explain Bathochromic shift and Hypsochromic shift.
2. Ilkovic equation.
3. Define quenching.
4. What is Junction potential?
5. Define the term retention time, retention volume.
6. Define Parent peak.
7. Define validation.
8. Give the range of I Spectrum.
9. What is edge effect?
10. Write different techniques in X-ray diffraction.



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