Download B.Pharm 4th Year 2020 December 564267 Formulative Pharmacy And Bio Pharmaceutics Question Paper

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(LR 4267)

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DECEMBER 2020 Sub. Code: 4267

(AUGUST 2020 SESSION)

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B.PHARM. DEGREE EXAMINATION

FOURTH YEAR

PAPER I ? FORMULATIVE PHARMACY AND BIO-PHARMACEUTICS

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Q.P. Code: 564267

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Time: Three hours

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Maximum: 100 Marks

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I. Elaborate on: (2 x 20 = 40)


1. Write the benefits and limitations of prolonged action pharmaceuticals. Discuss

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the different types, construction and evaluation of prolonged action
pharmaceuticals.


2. Define Pharmacokinetics and discuss the compartment models. Write a note on the

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following.
(a) Biological half life. (b) Apparent Volume of Distribution

(c) Elimination rate constant (d) Renal clearance.

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II. Write notes on:

(8 x 5 = 40)

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1. Mechanism of drug absorption.
2. Physicochemical properties of drug molecule.
3. Process of sugar coating.
4. Accelerated stability studies.

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5. Evaluation of Transdermal delivery systems.
6. Procedure for bio-equivalency studies.
7. Film defects and rectification.
8. Evaluation of hard gelatin capsules.

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III. Short answers on:

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(10 x 2 = 20)

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1. Lubricant and glidant.
2. Base absorption.
3. Hazing/ dull film.
4. Double impression.
5. Bio-pharmaceutics.

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6. Noyes Whitney equation.
7. Dielectric constant.
8. Slugging.
9. Different type of tablets.
10. Film tensile strength.

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