Download B.Pharm 4th Year 2022 January 564267 Formulative Pharmacy And Bio Pharmaceutics Question Paper

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[BPHARM 0122]

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JANUARY 2022

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Sub. Code: 4267

(AUGUST 2021 EXAM SESSION)

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B.PHARMACY DEGREE COURSE (NON-SEMESTER EXAMINATIONS)

FOURTH (FINAL) YEAR (Regulation 2009-2010)

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PAPER I ? FORMULATIVE PHARMACY AND BIO-PHARMACEUTICS

Q.P. Code: 564267

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Time: Three hours

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Answer ALL questions Maximum: 100 Marks

I. Elaborate on: (2 x 20 = 40)

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1. Discuss about Material and Manufacturing of Hard Gelatin Capsules and its

evaluation.

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2. Discuss the protocols followed for the studies of Bioavailability and Bioequivalence.

What are factors considered for the studies of Bio availability?

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II. Write notes on:

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(8 x 5 = 40)



1. Granulation methods.

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2. Processing problems of tablets.
3. Evaluation of Hard gelatin capsules.
4. Noyes-Whitney equation and its significance.
5. Co-acervation phase separation of Microencapsulation.
6. Volume of Distribution and elimination half life.

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7. Biological factors affecting drug absorption.
8. Measurement of Bioavailability.

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III. Short answers on:

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(10 x 2 = 20)

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1. Preformulation.
2. Compartmental models.

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3. Base adsorption.
4. Microencapsulation methods.
5. Types of Hardness tests.
6. Film coating polymers.
7. Slugging Process.

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8. Mechanism of drug absorption.
9. Benefits of Prolonged release dosage forms.
10. Renal clearance.

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