Download B.Pharm 4th Year 2013 August 564267 Formulative Pharmacy And Biopharmaceutics Question Paper

(LD 4267)

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AUGUST 2013

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Sub. Code: 4267

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FOURTH YEAR B.PHARM. EXAM

PAPER I ? FORMULATIVE PHARMACY AND BIOPHARMACEUTICS

Q.P. Code: 564267

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Time: Three Hours

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Maximum: 100 marks

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I. Elaborate on:

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(2X20=40)

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1. What are Preformulation Studies? Explain what physicochemical properties

of the drugs are determined in preformulation studies and their importance.

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2. Write on the different types of transdermal drug delivery systems and their

evaluation.

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II. Write notes on:

(8X5=40)

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1. Different types of tablets
2. Quality control tests on hard gelatin capsules
3. Film forming formulations in tablet film coating
4. Design of oral sustained release products

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5. Pan coating
6. Bioequivalency testing
7. Dosage form considerations in gastrointestinal absorption
8. Factors affecting stability of drug dosage forms

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III. Short Answers on:

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(10X2=20)



1. Components of a rotary punching machine

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2. Define bioavailability
3. Diluents used in tabletting
4. Storage Conditions to be maintained in standard stability testing
5. What is a fluidized bed processor?
6. What is meant by orange peel effect in tablet coating?

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7. Name tablet hardness testers
8. Relationship between biological half life and elimination rate constant in IV

bolus dosing following one compartment model

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9. Materials required for liposome preparation
10. What is an implant?

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