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AUGUST 2013
Sub. Code: 4267
PAPER I ? FORMULATIVE PHARMACY AND BIOPHARMACEUTICS
Q.P. Code: 564267
Time: Three Hours
Maximum: 100 marks
I. Elaborate on:
1. What are Preformulation Studies? Explain what physicochemical properties
of the drugs are determined in preformulation studies and their importance.
evaluation.
(8X5=40)
1. Different types of tablets
2. Quality control tests on hard gelatin capsules
3. Film forming formulations in tablet film coating
4. Design of oral sustained release products
6. Bioequivalency testing
7. Dosage form considerations in gastrointestinal absorption
8. Factors affecting stability of drug dosage forms
III. Short Answers on:
1. Components of a rotary punching machine
3. Diluents used in tabletting
4. Storage Conditions to be maintained in standard stability testing
5. What is a fluidized bed processor?
6. What is meant by orange peel effect in tablet coating?
8. Relationship between biological half life and elimination rate constant in IV
bolus dosing following one compartment model
10. What is an implant?
AUGUST 2013
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Sub. Code: 4267
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FOURTH YEAR B.PHARM. EXAMPAPER I ? FORMULATIVE PHARMACY AND BIOPHARMACEUTICS
Q.P. Code: 564267
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Time: Three Hours
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Maximum: 100 marks
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I. Elaborate on:
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(2X20=40)--- Content provided by FirstRanker.com ---
1. What are Preformulation Studies? Explain what physicochemical properties
of the drugs are determined in preformulation studies and their importance.
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2. Write on the different types of transdermal drug delivery systems and theirevaluation.
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II. Write notes on:(8X5=40)
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1. Different types of tablets
2. Quality control tests on hard gelatin capsules
3. Film forming formulations in tablet film coating
4. Design of oral sustained release products
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5. Pan coating6. Bioequivalency testing
7. Dosage form considerations in gastrointestinal absorption
8. Factors affecting stability of drug dosage forms
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III. Short Answers on:
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(10X2=20)1. Components of a rotary punching machine
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2. Define bioavailability3. Diluents used in tabletting
4. Storage Conditions to be maintained in standard stability testing
5. What is a fluidized bed processor?
6. What is meant by orange peel effect in tablet coating?
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7. Name tablet hardness testers8. Relationship between biological half life and elimination rate constant in IV
bolus dosing following one compartment model
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9. Materials required for liposome preparation10. What is an implant?
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