Rajiv Gandhi University of Health Sciences, Karnataka
Fellowship Examination — 13-Feb-2024
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Time: Three Hours Max. Marks: 100 Marks
ONCO PHARMACY - PAPER -1
QP Code: 4328
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
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Answer All The Questions 10 X 10 = 100 Marks
- Describe cell cycle with illustration; what are CDK4-6 inhibitors and mention how they differ from each other?
- Explain the Umbrella design of clinical trial with a suitable example
- Discuss the different bioformulations of Paclitaxel and its uses
- Explain the concept of chemoradiation with suitable examples
- Define adjuvant chemotherapy and the scientific basis for the same. In which cancers has it made a survival impact
- What is Monoclonal Antibody? Name five monoclonal antibodies in clinical use, its target and how do you select patients for the same
- Mention the different TKI's available for treatment of e GFR mutated lung cancer and how they differ from each other
- Mention the drugs that cause SIADH and how does it present clinically. Discuss the management of the same
- Write the chemotherapy schedule and any specific instructions, for a patient of Hodgkin’s Lymphoma, planned for treatment with ABVD protocol, aged 25 years, height 168 cms, weight 58 kgs. How do you manage extravasation of drugs?
- Name the LHRH Agonists and LHRH Antagonists and their mechanism of action. What are the indications and how do you select them in a given patient?
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