? Identification of lymphoid tissue under the microscope
? Microanatomy of lymph node, spleen, thymus, tonsil and correlation of structure with
function
Topic: Bone and Cartilage (AN71.1 to AN71.2)
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? Identification of bone under the microscope? Types and structure-function correlation of bone
? Identification of cartilage under the microscope
? Types and structure function correlation of cartilage
Topic: Integumentary System (AN72.1)
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? Identification of skin and its appendages under the microscope? Correlation of structure and function
C. GENETICS
Topic: Chromosomes (AN73.1 to AN73.3)
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? Structure of chromosomes with classification? Technique of karyotyping with its applications
? Lyon's hypothesis
Topic: Patterns of Inheritance (AN74.1 to AN74.4)
? Various modes of inheritance with examples
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? Pedigree charts for the various types of inheritance? Examples of diseases of each mode of inheritance
? Multifactorial inheritance with examples
? Genetic basis and clinical features of achondroplasia, cystic fibrosis, vitamin D resistant
rickets, haemophilia, Duchenne's muscular dystrophy and sickle cell anaemia*
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Topic: Principle of Genetics, Chromosomal Aberrations and Clinical Genetics (AN75.1 toAN75.5)
? Structural and numerical chromosomal aberrations
? Mosaics and chimeras with examples
? Genetic basis and clinical features of Prader Willi syndrome, Edward syndrome and Patau
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syndrome*? Genetic basis of variation: polymorphism and mutation
? Principles of genetic counselling
D. GENERAL EMBRYOLOGY
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Topic: Introduction to embryology (AN76.1 TO AN76.2)? Stages of human life
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? Terms - phylogeny, ontogeny, trimester, viability
Topic: Gametogenesis and fertilization (AN77.1 to AN77.6)
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? Uterine changes occurring during the menstrual cycle? Synchrony between the ovarian and menstrual cycles
? Spermatogenesis and oogenesis
? Stages and consequences of fertilization
? Anatomical principles underlying contraception
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? Teratogenic influences; fertility and sterility, surrogate motherhood, social significance of"sex-ratio"*
Topic: Second week of development (AN78.1 to AN78.5)
? Cleavage and formation of blastocyst
? Development of trophoblast
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? Process of implantation and common abnormal sites of implantation? Formation of extra-embryonic mesoderm and coelom, bilaminar disc and prochordal plate
? Abortion, decidual reaction, pregnancy tests
Topic: 3rd to 8th week of development (AN79.1 to AN79.6)
? Formation and fate of the primitive streak
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? Formation and fate of notochord? Process of neurulation
? Development of somites and intra-embryonic coelom
? Embryological basis of congenital malformations, nucleus pulposus, sacrococcygeal
teratomas, neural tube defects
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? Diagnosis of pregnancy in first trimester*? Role of teratogens, alpha-fetoprotein*
Topic: Fetal membranes (AN80.1 to AN80.7)
? Formation, functions and fate of chorion, amnion, yolk sac, allantois and decidua
? Formation and structure of umbilical cord
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? Formation of placenta, its physiological functions, foeto-maternal circulation and placentalbarrier
? Embryological basis of twinning in monozygotic and dizygotic twins
? Role of placental hormones in uterine growth and parturition
? Embryological basis of estimation of fetal age*
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? Types of umbilical cord attachments*Topic: Prenatal Diagnosis (AN81.1 to AN81.3)
? Methods of prenatal diagnosis
? Indications, process and disadvantages of amniocentesis
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? Indications, process and disadvantages of chorion villus biopsy23