functions of ovary and its control, menstrual cycle: Hormonal, uterine and ovarian changes; Tests
for ovulation; Physiological effects of sex hormones; Contraceptive methods for male and female;
Effects of removal of gonads on physiological functions; Physiology of pregnancy, fetoplacental
unit, pregnancy tests, parturition & lactation; Semen analysis; Causes and principles of
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management of infertility; Hormonal changes and their effects during perimenopause andmenopause; Psychological and psychiatric disturbances associated with reproductive
physiology.
Neurophysiology: (PY 10.1 - 10.20)
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(37 hrs)
Organization of nervous system; Sensory system: types, functions and properties of synapse,
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receptors, reflex; Somatic sensations & sensory tracts; Physiology of pain; Motor system:organization, motor tracts, mechanism of maintenance of tone, control of voluntary movements ;
Posture and equilibrium & vestibular apparatus; Reticular activating system, Autonomic nervous
system ; Spinal cord: functional organization and lesions ; Formation, circulation and function of
CSF; Blood brain barrier; Neurotransmitters.
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Organization, connections and functions of cerebral cortex, basal ganglia, thalamus,hypothalamus, cerebellum and limbic system and their abnormalities; Higher mental functions ;
Physiology of sleep, memory, learning and speech and their disorders; EEG.
Special senses- Smell and taste sensation and their abnormalities; Functional anatomy of ear and
auditory pathways & physiology of hearing, Deafness, hearing tests; Functional anatomy of eye,
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Image formation, Visual pathway and its lesions, Physiology of vision including acuity of vision,colour vision, field of vision, refractive errors, physiology of pupil; light reflex, accommodation
reflex, dark and light adaptation; Auditory & visual evoked potentials
Integrated Physiology: (PY 11.1 - 11.14)
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(6 hrs)
Temperature regulation: mechanism, adaptation to altered temperature (heat and cold
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environment), mechanism of fever, cold injuries and heat stroke; Exercise- cardio-respiratory andmetabolic adjustments during exercise (isotonic and isometric), exercise in heat and cold, physical
training effects; Physiological consequences of sedentary lifestyle; Brain death; Physiology of
Infancy*; Physiology of aging-free radicals and antioxidants*; Physiology of meditation*.
(* `Non-core' competencies as per "Competency based Undergraduate Curriculum for the Indian
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Medical Graduate 2018: Medical Council of India").PRACTICAL
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The following list of practical is minimum and essential. Additional exercises can be included as
and when feasible and required. All the practicals have been categorized as 'Procedures to be
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performed' and 'Demonstrations'. The procedures are to be performed by the students duringpractical classes to acquire skills. These would be included in the practical during University
examination. Those categorized as `Demonstrations' are to be shown to students during practical
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classes. Questions based on these would be given in the form of data, charts, graphs, problems
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and case histories for interpretation by students during university examination.I.Procedures to be performed by the students:
a.
Haematology:
1. RBC count
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2. WBC Count3. Differential Leucocyte Count
4. Estimation of haemoglobin
5. Blood grouping
6. Bleeding time
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7. Clotting time8. Calculate RBC indices - MCV, MCH, MCHC.
b. Procedures to be performed on human subjects:
1. Mosso's ergography.
2. Recording of Blood Pressure, pulse rate at rest and effect of posture.
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3. Effect of mild and moderate exercise on blood pressure, pulse rate and respiratory rateusing Harvard step test.
4. Record and interpret Lead II ECG. Given a normal ECG, determine cardiac axis.
5. Spirometry ? Lung volumes and capacities, MVV, Timed vital capacity.
6. Peak Expiratory Flow Rate
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7. Demonstrate Basic Life Support in a simulated environment8. Visual field by Perimetry
c. Clinical Examination:
1. Components of history taking and general physical examination
2. Examination of radial pulse
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3. Examination of Cardiovascular system4. Examination of Respiratory system
5. Examination of abdomen
6. Examination of Higher mental functions
7. Examination of Sensory system
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8. Examination of Motor system including reflexes.9. Examination of Cranial Nerves
II. Demonstrations:
I.Haematology:
1. Erythrocyte sedimentation rate
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2. Haematocrit3. Reticulocyte count
4. Platelet count
5. Osmotic fragility
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2.
Record Arterial pulse tracing using finger plethysmography*
3.
Stethography
4.
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Tests of cardiovascular autonomic functions*(* `Non-core' competencies as per "Competency based Undergraduate Curriculum for the
Indian Medical Graduate 2018: Medical Council of India")
III. Interpretation- charts: clinical case histories, graphs, charts, problems
(Suggested topics for preparation of these are given under ANNEXURE I. However, many more
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could be developed which is under discretion of each institution)Chart also includes - Interpret growth chart*, Interpret anthropometric assessment of infants*:
(*these two charts are `Non-core' competencies as per "Competency based Undergraduate
Curriculum for the Indian Medical Graduate 2018: Medical Council of India")
IV. Computer assisted learning:
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(i) Amphibian nerve - muscle experiments and interpretation of graphsList of graphs on nerve-muscle experiments:
? Simple muscle twitch
? Effect of various strengths of stimuli on Simple muscle twitch
? Effect of changes in temperature on Simple muscle twitch
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? Effect of two successive stimuli on muscle contraction? Effect of multiple successive stimuli (treppe, clonus, tetanus)
? Study of fatigue in skeletal muscle
? Velocity of nerve conduction
? Effect of load on muscle
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? Measurement of isometric contractions using nerve muscle preparation(ii) Amphibian cardiac experiments and interpretation of graphs
List of graphs on cardiac experiments:
? Normal cardiogram
? Effect of temperature on frog heart
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? Effect of Stannius ligatures? Properties of cardiac muscle ? all or none law, staircase effect, refractory period in a
beating heart (extrasystole and compensatory pause), refractory period in a quiescent
heart
? Effect of vagus on frog's heart
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? Action of drugs on vagus (nicotine and atropine)? Perfusion of isolated heart and effect of ions (NaCl, KCl, CaCl2)
? Perfusion of isolated heart and effect of drugs (adrenaline, acetyl choline, atropine
followed by Ach)
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