Date: 06-10-2013
K 4105
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
Instructions: 1. Answer to the points. 2. Figure
to the right indicates marks. 3. Use separate
answer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.
1. Give an account of: (any two) (10)
a) Atherosclerosis and significance of high
density lipoprotein (A. 228, 222)(C. 326, 320)
b) Glycogen storage diseases (A. 144) (C.269)
account of various factors affecting enzyme
activity
2. Write Short notes on (any three) (9)
a) Enzyme inhibition (A. 63) (C.92)
c) Disaccharides
d) Functions of cholesterol
e) Porphyrias (A. 328) (C.212)
3. Write Short notes on (any two) (6)
b) Metabolic acidosis (A. 402) (C.481)
c) Composition of urine
Section 2
4. Give an account on (any two) (10)
importance (A. 525) (C. 640)
b) Glycogenolysis and its regulation (A. 140)
(C.265)
c) Oxidation of odd-chain fatty acids,
5. A. Write Short notes on (any three) (9)
a) Carcinogens
b) Regulation of fatty acid synthesis
c) Importance of bile salts in digestion and
d) Clinical importance of HMP shunt
e) Health hazard of water pollution
6. Read the following case and answer the
questions in two or threee lines only.: Any
six of the following: A middle aged
businessman aged 42 years was brought to
(6)
Dharpur civil hospital in semicomatoses patient
was a known case of NIDDM. He did not take
Ophthalmic checkup revealed cataract in both
cycs. Lab Report of blood sample taken at the
time of admission Random plasma glucose -
>45 mgs% 31cod ph->7.30, urine sugar ->
patient
a) Mention the likely cause of low blood ph in
this patient
b) Name ketone Bodies excreted in patient's
c) Mention 2-3 differences between NIDDM and
IDDM
d) Mention the reason for polyuria in this patient
e) Why glucose level was elevated in this
patient?
f) What is glycosylated Hb? Why it is often
estimated in patients of Diabetes Mellitus
g) Mention the name of hormone that brings
down blood glucose level in human being
***
K 4105
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
--- Content provided by FirstRanker.com ---
Max Marks: 50Instructions: 1. Answer to the points. 2. Figure
to the right indicates marks. 3. Use separate
answer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.
--- Content provided by FirstRanker.com ---
Section 11. Give an account of: (any two) (10)
a) Atherosclerosis and significance of high
density lipoprotein (A. 228, 222)(C. 326, 320)
b) Glycogen storage diseases (A. 144) (C.269)
--- Content provided by FirstRanker.com ---
c) Discuss how enzymes is classified? Write anaccount of various factors affecting enzyme
activity
2. Write Short notes on (any three) (9)
a) Enzyme inhibition (A. 63) (C.92)
--- Content provided by FirstRanker.com ---
b) Classification of lipidsc) Disaccharides
d) Functions of cholesterol
e) Porphyrias (A. 328) (C.212)
3. Write Short notes on (any two) (6)
--- Content provided by FirstRanker.com ---
a) Renal function test (A. 370) (C. 459)b) Metabolic acidosis (A. 402) (C.481)
c) Composition of urine
Section 2
4. Give an account on (any two) (10)
--- Content provided by FirstRanker.com ---
a) Conjugation reaction in Detoxification and itsimportance (A. 525) (C. 640)
b) Glycogenolysis and its regulation (A. 140)
(C.265)
c) Oxidation of odd-chain fatty acids,
--- Content provided by FirstRanker.com ---
mentioning the role of Vit-B125. A. Write Short notes on (any three) (9)
a) Carcinogens
b) Regulation of fatty acid synthesis
c) Importance of bile salts in digestion and
--- Content provided by FirstRanker.com ---
absorption of fatsd) Clinical importance of HMP shunt
e) Health hazard of water pollution
6. Read the following case and answer the
questions in two or threee lines only.: Any
--- Content provided by FirstRanker.com ---
six of the following: A middle aged
businessman aged 42 years was brought to
(6)
Dharpur civil hospital in semicomatoses patient
was a known case of NIDDM. He did not take
--- Content provided by FirstRanker.com ---
antidiabetogenic drug for last 20-25 days.Ophthalmic checkup revealed cataract in both
cycs. Lab Report of blood sample taken at the
time of admission Random plasma glucose -
>45 mgs% 31cod ph->7.30, urine sugar ->
--- Content provided by FirstRanker.com ---
++++ Ketone Bodies detected in urine sample ofpatient
a) Mention the likely cause of low blood ph in
this patient
b) Name ketone Bodies excreted in patient's
--- Content provided by FirstRanker.com ---
urinec) Mention 2-3 differences between NIDDM and
IDDM
d) Mention the reason for polyuria in this patient
e) Why glucose level was elevated in this
--- Content provided by FirstRanker.com ---
patient?
f) What is glycosylated Hb? Why it is often
estimated in patients of Diabetes Mellitus
g) Mention the name of hormone that brings
down blood glucose level in human being
--- Content provided by FirstRanker.com ---
h) lodine deficiency leads to Goitre***