First Year MBBS Examination
I MBBS Biochemistry Paper 2
Time: 3 hours Date: 06-12-2013 Max Marks: 50
Instructions: 1. Answer to the points. 2. Figure
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to the right indicates marks. 3. Use separateanswer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.
Section 1
1. Give an account of: (any two) (10)
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a. Recombinant DNA technology and its usesin clinical medicine (A. 600) (C. 579)
b. Write various inbom errors of aromatic
amino acid
c. DNA replication process and its inhibitors
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(A. 559, 565) (C. 524, 528)2. Write Short notes on (any three) (9)
a. t-RNA (A. 578) (C. 81)
b. Mutation (A. 591) (C.535)
c. Gene expression
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d. Post transcription modification (A. 572) (C.547)
e. Biological significance of nucleotides
3. Write Short notes on (any two) (6)
a. Basal metabolic rate (BMR) (A. 512)
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(C.504)b. Marasmus and Kwashiorkor (C.516)
c. Metabolic adaptation in fed and starvation
state (A. 122) (C. 383)
Section 2
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1. Give an account on (any two) (10)a. Classification of proteins with example (A.
43) (C. 63)
b. Iron
c. Formation of ammonia and its fate (A. 257)
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(C.335)2. Write Short notes on (any three) (9)
a. One carbon metabolism (A. 262) (C.363)
b. Rhodopsin cycle (A. 454) (C.129)
c. Salvage pathway of purine (A. 546) (C.
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391)d. Gout (A. 548) (C. 394)
e. Pernicious anaemia
3. Write Short notes of (any six) (6)
a. Replication in semi-conservative
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b. Tyrosine is an essential amino acid forpatients of phenylketonuria
c. DNA finger printing can reveal the identity
of a person
d. In vitamin C deficiency there is delayed
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wound healinge. Proteins can be separated by
electrophoresis
f. lodine deficiency leads to Goitre
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