125irst Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
Max
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Marks: 50Instructions: 1. Answer to the points. 2. Figure
to the right indicates marks. 3. Use separate
answer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.
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Section 11. Give an account of: (any two) (10)
a. Write briefly about isoenzyme and their
clinical significance
b. Write about normal acid bade mechanism
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in our bodyc. Write briefly about homeostasis of body
fluids in human
2. Write Short notes on (any three) (9)
a. Kidney function test
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b. Gluconeogenesis (A. 135) (C.258)c. Plasma membrane transport
d. Tumor markers (A. 666) (C.691)
e. Disaccharides
3. Write Short notes on (any two) (6)
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a. Coenzymes and biochemical reactionsb. Porphyria
c. Chromatography (A. 434) (C.719)
Section 2
1. Give an account on (any two) (10)
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a. Describe reactions energetic importanceand regulation of Citric acid cycle
b. What are Lipoproteins? Explain the role of
HDL in lipoprotein metabolism (A. 217) (C.
317)
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c. Explain electron transport chain and itsinhibitors (A. 315, 318) (C. 226,232)
2. Write Short notes on (any three) (9)
a. Significance of HMP shunt (A. 144) (C.
270)
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b. Structure and functions ofImmunoglobulins (A. 649) (C.186)
c. Air pollutants and their adverse effects (A.
534) (C.663)
d. Oncogenic viruses
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e. Ketone bodies3. Write notes of (any six): A 45 year old obese
business man with complaint of excessive
hunger, thirst urination and non-healing injury
of lower leg was consulted by physician
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before starting treatment suggest. (6)a. What is the problem diagnosis justify
b. What investigations to be done in blood for
confirmation of diagnosis?
c. What investigations to be done in urine
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sample?d. Suggest special investigations for
monitoring during treatment.
e. What is the reason for excessive hunger,
thirst and urination?
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f. What is the reason for non-healing injury?g. Indicate other abnormalities likely to be
developed if disease is not properly
managed.
h. What advice regarding diet to be given?
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