First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours Max Marks: 50
Date: 12-10-2014
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Instructions: 1. Answer to the points. 2. Figureto the right indicates marks. 3. Use separate
answer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.
Section 1
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1. Give an account of: (any two) (10)a) Role of Kidney in acid base regulation
b) What are the different types of enzymes
inhibitors? Explain with suitable examples
c) Mention the various types of abnormal
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hemoglobin and discuss sickle cell disease2. Write Short notes on (any three) (9)
a) Lipoproteins (A. 217) (C. 317)
b) Mucopolysaccharides (A. 98) (C. 22)
c) Fluid Mosaic model (A. 13)(C.650)
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d) Jaundice (A. 332) (. 216)e) Mucopolysaccharides
3. Write Short notes on (any two) (6)
a) Liver function test (LFT)
b) Electrophoresis and its importance (A. 432)
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(C.724)c) Active transport (A. 15) (C. 651)
Section 2
4. Give an account on (any two) (10)
a) Metabolism of ketone bodies
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b) Glycogen storage diseases (A. 144) (C.269)c) Regulation and significance of
gluconeogenesis (A. 135) (C.258)
5. A. Write Short notes on (any three) (9)
a) Free radical scavenging enzymes
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b) Inhibitors of electron transport chain (A. 315,318) (C. 226, 232)
c) Lead poisoning
d) Oncogenes (A. 664) (C.687)
e) Functions of immunoglobulin (A. 649)
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(C.186)6. Write Short notes of (any six) (6)
a) LDL is bad cholesterol and HDL is good
cholesterol
b) Glucose is not formed in muscle
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glycogenolysisc) Temperature affects enzymes activity
d) Glucose 6 phosphate dehydrogenase
deficiency causes hemolytic anaemia
e) Prostaglandins act as detoxifying agent (A.
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243) (C.644)
f) Role of glutathione as detoxifying agent
g) Methotrexate is an anticancer drug
h) Primary excess of carbonic acid causes
respiratory acidosis
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***Document Outline
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