Date: 11-12-2014
First Year MBBS Examination
I MBBS Biochemistry Paper 2
Time: 3 hours
Max

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Marks: 50
Instructions: 1. Answer to the points. 2. Figure
to the right indicates marks. 3. Use separate
answer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.

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Section 1
1. Write short notes on: (any two) (10)
a. DNA Replication and its inhibitors
b. PCR technique and its application
c. Metabolic adaptation during fed and

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starvation
2. Write Short notes on (any three) (9)
a. Mutation
b. Posttranscriptional modifications

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c. Urea cycle

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d. t-RNA
3. Write Short notes on (any two) (6)
a. BMR
b. Marasmus
c. Blotting technique

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Section 2
1. Write Short notes on (any two) (10)
a. Formation of ammonia and its faie
b. Hyperuricemia
c. Classification of proteins with examples

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2. Write Short notes on (any three) (9)
a. Selenium
b. Antioxidant vitamins
c. Methyl folate trap
d. One carbon metabolism

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3. Write Justification of following statements:
(any six) (6)
a. Ethanol is antidote of methanol poisoning
b. Glycolysis is in RBC ends in lactate
production

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c. Tyrosine is an essential amino acid for
patients of phenylketonuria
d. Calcium deficiency leads to osteomalacia
e. Very high temperature decrease enzymes
activity

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f. Hyperventilation causes metabolic
alkalosis
g. Cellulose cannot be digested and absorbed
by human
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