Date: 05-12-2014
Preli
First Year MBBS Examination
I MBBS Biochemistry Paper 2
Time: 3 hours

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Max Marks: 50
Instructions: 1. Answer to the points. 2. Figure
to the right indicates marks. 3. Use separate
answer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.

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Section 1
1. Write short notes on: (any two) (10)
a. PCR technology its advantages & medical
applications
b. DNA Replication

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c. Metabolic adaptation during fed & starvation
2. Write Short notes on (any three) (9)
a. Genetic code
b. Lac operon
c. Post transcriptional modifications

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d. Structure of t RNA
e. Mutations
3. Write Short notes on (any two) (6)
a. BMR
b. Digestion & absorption of fats

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c. Obesity

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Section 2
4. Write Short notes on (any two) (10)
a. Fate of Ammonia
b. Hyperuricemia & Gout

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c. Phenylalanine metabolism & related
disorders
5. Write Short notes on (any three) out of five)
(9)
a. Purine Salvage pathway

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b. Beri Beri
c. Biological functions of Selenium
d. Tertiary Structure of protein
e. Deficiency manifestations of Vitamin B12
6. Write Justification of following

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statements:any six) (6)
a. Calcium deficiency leads to Osteomalacia
b. Decrease activity of Telomerase can be one
of the reason of aging
c. Very high temperature decrease enzyme

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activity
d. Methylation of DNA is important in
functioning of mismatch repair
e. Uronic acid pathway is related with
detoxification

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f. Hyperventilation causes metabolic alkalosis
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Document Outline

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