Preli
First Year MBBS Examination
I MBBS Biochemistry Paper 2
Time: 3 hours
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Max Marks: 50Instructions: 1. Answer to the points. 2. Figure to the
right indicates marks. 3. Use separate answer books
for each section. 4. Draw diagrams wherever
necessary. 5. Write legibly.
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Section 11.Write short notes on: (any two) (10)
a) Hyperuricema & Gout
b) Replication and its inhibitors
c) PCR technique & its medical application
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2.Write Short notes on (any three) (9)a) Genetic Code
b) Mutation
c) Blotting technique
d) Structure & functions of t-RNA
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3.Write Short notes on (any two) (6)a) Metabolic adaptation during fed
b) BMR
c) Protein energy malnutrition (PEM)
Section 2
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4.Write Short notes on (any two) (10)a) Urea cycle & its inbom errors
b) Plasma protiens & their clinical significance
c) Blood calcium regulation
5.Write Short notes on (any three) out of five) (9)
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a) Biochemical functions of vitamin Db) Antioxidant vitamins
c) Salvage pathway of purines & its importance
d) One carbon metabolism
e) Deficiency manifestations of Vitamin B12
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6.Write Justification of following statements(anysix) (6)
a) Hyperuricemia is seen in patients of leukemia on
chemotherapy
b) Vitamin B12 deficiency leads to folate trap
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c) Same RNA acts as enzymesd) Nucleotide analogues are used in treatment of
cancer
e) Chargaff's rule is applicable in DMA but not in
RNA
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f) Urine of alkaptonuria patients turns black onexposure to air
g) Deficiency of a antitrypsin can cause emphysema
h) Vitamin E & Se acts synergistically
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