First Year MBBS Examination
I MBBS Biochemistry Paper 2
Time: 3 hours Max Marks: 50
Date: 12-12-2018
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Instructions: 1. Answer to the points. 2. Figureto the right indicates marks. 3. Use separate
answer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.
Section 1
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1.Write short notes on: (any two) (10)a. Recombinant DNA Technology and its
applications (A. 600) (C. 579)
b. DNA repair mechanism (A. 562) (C. 537)
c. Gout (A. 548) (C. 394)
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2.Write Short notes on (any three) (9)a. Post Transcriptional Modification (A. 572)
(C. 547)
b. Lac operon (A. 595) (C.567)
c. Gene Therapy (A. 604) (C.625)
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d. Mutation (A. 591) (C.535)e. Use of Radio Isotopes in Medicine (A. 682)
(C. 717)
3.Write Short notes on (any two) (6)
a. Importance of dietary fibers (A. 515) (C. 510)
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b. Metabolic adaptation in Starvation (A. 122)(C. 383)
c. Fate of Acetyl Co A
Section 2
4.Give an account on (any two) (10)
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a. Classification of amino acids (A. 24) (C. 44)b. Sources and functions of copper. Add a note
on Wilson's disease
c. Specialized products synthesized from
Tyrosine
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5.Write Short notes on (any three) (9)a. Wald's visual cycle (A. 454) (C. 121)
b. Salvage pathway of purine nucleotides (A.
546) (C. 391)
c. Functions of Vitamin B1
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d. Causes and deficiency manifestations of folicacid (A. 475) (C. 151)
e. Degradation of pyrimidine nucleotides (A.
551) (C.400)
6.Comment and justify the following:(any six)
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(6)a. Electrophoresis of serum proteins is useful in
diagnosis of clinical diseases (A. 384)
(C.724)
b. Selenium and vitamin E acts synergistically
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c. HMP shunt is necessary for de novosynthesis of purine nucleotide
d. Vitamin B12 is protective against ischemic
heart disease
e. Hemolysed sample should not be used for
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potassium estimation in laboratory.f. c-AMP plays a vital role in action of certain
hormones
g. Chronic liver disease causes edema
h. Some type of mushrooms are poisonous.
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***Document Outline
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