Second Year MBBS Examination
II MBBS Microbiology Paper 2 (New)
Date: 03-01-2023
Time: 2 hours
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Instructions: 1. Answer to the points.2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.
5. Write legibly.
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Section 1Max Marks: 50
1. Structured Long Question: (Any 1 out of
2) (10)
a) 18-year-old young female was admitted to
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the hospital with intense headache, abdominaldiscomfort for last 5 days. She had also
developed fever which is of remittent type with
gradual rise in a step ladder fashion, on
examination she was toxic with temperature of
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101 F, Tongue was coated and mildsplenomegaly was present.
(a) What is most probable etiological
diagnosis? (b) Describe pathogenesis of this
condition. (c) Describe lab diagnosis. Write note
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on treatment and prevention.b) A 54-year old male was admitted to the
hospital with complaints of severe pain in lateral
aspect of his left calf and small amount of pus
discharge from ingrown hair. On physical
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examination, the local area was found to be red,warm and tender pus was aspirated and was
subjected to gram stain (Showed gram positive
cocci in cluster) culture on blood agar showed B
haemolytic colony.
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(a) What is the clinical diagnosis and causativeorganism?(b) Enlist the infections caused by
causative organism.(c)Enlist the virulence
factors of this organism and lab diagnosis of
the organism.2+3+5
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2. Short notes: (Any 2 out of 3) (12)a) Laboratory diagnosis of Gas gangrene
b) Clinical feature and laboratory diagnosis of
Malaria
c) Aspergillosis
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3. Short notes: (Any 3 out of 4) (18)a) Extra intestinal amoebiasis.
b) Laboratory diagnosis of Dermatophytes
c) Histoplasmosis
d) Clinical feature and laboratory diagnosis of
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Bacterial meningitis.4. Answer only in 2-3 sentences: (Any 5 out
of 6) (10)
a) Enumerate four bacteria causing sexual
transmitted infection.
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b) Clinical characteristics of mycetoma.c) Enumerate 4 fungus which infects CNS.
d) Difference between Tuberculoid and
Lepromatous leprosy.
e) Name two fungi causing food poisoning.
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f) Clinical feature of Enteric fever.Section 2
Max Marks: 50
5. Structured Long Question: (Any 1 out of
2) (10)
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a) A child aged 7 years with high grade fever,toxic, pain in the throat, inability to swallow was
brought to the casualty. On examination a white
patch was found on the fauces, which started
bleeding when touched. No history of
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immunization is available. (1) What is clinicaldiagnosis? (2) Name the etiological agent
causing this clinical condition. (3) Write in detail
pathogenesis and laboratory diagnosis of this
condition. (4) Discuss the management of this
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condition.1+1+6+2b) A 28-year-old male having history of sexual
exposure with commercial sex worker is
presented to a STD clinic with painless hard
indurated genital ulcer and painless hard lymph
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node. (1) What is the probable condition andetiological agent? (2) Describe in detail the
pathogenesis of this condition. (3) Describe
laboratory diagnosis of above clinical condition
2+4+4
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6. Short notes: (Any 2 out of 3) (12)a) Opportunistic infection of AIDS.
b) Enumerate oncogenic viruses. Describe any
one in detail.
c) Morphology & pathogenesis of HIV/AIDS.
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7. Short notes: (Any 8 out of 4) (18)a) Clinical features and laboratory diagnosis of
Round worm infection.
b) Clinical features and laboratory diagnosis of
central nervous system infection.
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c) Clinical features and laboratory diagnosis ofHepatitis B virus infection.
d) Clinical features and laboratory diagnosis of
food poisoning.
8. Answer only in 2-3 sentences: (Any 5 out
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of 6) (10)a) Enumerate 2 parasites infecting
Hepatobiliary system.
b) Enumerate 2 organisms causing lobar A
pneumonia.
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c) Morphological classification of fungi.d) Clinical characteristics of Rabies
e) Describe string test.
f) Enumerate four systemic mycoses.
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