Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
Max Marks: 40
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Date: 01-04-2015Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
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4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1.MCQ (10)
a. An Ultrashort acting Beta blocker is (A)Atenolol (B)
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Betaxotol (C)Esmolol (D)Pindotolb. An alpha-2 receptor blocker is (A)Yohimbine (B)
Tamsulosin (C)Prazosin (D)Labetalol.
c. This drug does not cross blood brain barrier (a)
Dopamine (b)Scopolamine (A) Clonidine
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(d)Physostigmined. An antidote for diazepam overdose is (a) Flunazenil
(b) Rimelteon (c) Melatonin (d) Amphetamine
e. All of the following are the uses of Carbamazepine
EXCEPT-(a) Manic Depressive Tiness (b)
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Generalised Tonic-Clonic Seizures (c) AbsenceSeizures d) Trigeminal Neuralgia
f. ADrg for migraine prophylaxis i is-a) Sumatriptan
(by Propanolol(c) Ergotamine (d) Naproxen
g. An antihistaminic agent used in vertigo is (a)
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Dimenhydrinate (b) Loratadine (c) Mizolastine (a)Rupatadine
h. Spironolactone should not be given with (a) Loop
acting Diuretics (b) ACEInhibitors (c) Calcium
Channel Blockers (d)Organic Nitrates
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i. A Calcium channel blocker which causesbradycardia is-(a) Verapamil (b) Amle dipine (c)
Nifedipine(d)Nicardipine
j. Extrayramidal reactions can occur with the use of-
(a) Antidepressants (b) Antiepileptics (c)
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Antipsychistios (d)AnxiolytiesSection 2
2.Write Short Notes on (Four out of Five) (10)
a. Clearance
b. Dicyelomine-
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c. Half Life of a drugd. Atenolol
e. Cetirizine
3.Briefly Describe the pharmacological basis of
use of-(Four out of Five) (10)
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a. Atropine in organophosphate poisoningb. Neostigmine in Myasthenia gravis
c. Dopamine-in shock
d. Methotrexate in rheumatoid arthritis
e. Diazepam in status epilepticus
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4.Briefly Describe (Any Two out of Three) (10)a. Angiotensin Converting Enzyme Inhibitors(ACE-Is)
b. Loop Acting Diuretics
c. Organic Nitrates
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