Second Year MBBS Examination
II MBBS Pharmacology Paper 1 (New)
Time: 3 hours
Max Marks: 100
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Date: 04-01-2023Instructions: 1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.
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5. Write legibly.Section 1
1. Structured long question: (any 1 out of 2) (10)
a. Mention all the routes of drug administration.
Write in details about parenteral routes of
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drug administration.b. Classify antidepressant drugs. Write in
details about pharmacological actions and
adverse effects of Tricyclic Antidepressants
(TCAS).
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2. Case based scenario / Applied short notes:(any 2 out of 3) (12)
3. Write short notes: (any 3 out of 4) (18)
a. Write differentiating features between
competitive and non-competitive
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neuromuscular blocking agents.b. Mechanism of action and adverse effects of
phenytoin.
c. Fundamental principles of bioethics.
d. Uses and techniques of local anaesthesia.
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4. Answer only in 2-8 sentences: (any 5 out of 6)(10)
a. Define plasma half-life. Write status of half-
life in first and zero order kinetics.
b. Mention any four non cardiac uses of beta
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blockers.c. Write any four examples of atypical
antipsychotics,
d. Enlist any four uses of centrally acting
muscle relaxants
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e. Write any four contraindications of adrenalinf. Name all the phases of clinical trial.
Section 2
1. Structured long question: (any 1 out of 2) (10)
a. Mention drugs used in treatment of heart
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failure. Write in details about mechanism ofaction of adverse effects of digoxin.
b. Classily diuretics. Write in details about uses
and complications of high ceiling and thiazide
type of diuretics
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2. Case based scenario / Applied short notes:(any 2 out of 3) (12)
a. 55 years old male patient presented with
complain of chest pain while doing exercise
and not at rest since 15 days. On further
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detailing he revealed that he is chronicsmoker. (a) Give your provisional diagnosis.
(b) Name the drugs which can be used to
treat this clinical condition? (c) Justify
combinations of drugs used in this clinical
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condition.b. 25 years old female reported complain of
headache since last one week. Headache
was unilateral and pulsatile in nature. Further
she told that it usually last up to 6 hours in a
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day and it is first time she has experiencedsuch headache. (a) Give your provsional
diagnosis. (b) What treatment and
precautions you will advise to this patient ?
(c) Name all the drug which can be used to
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treat and prevent this clinical condition.
c. Write in details about choice of Nonsteroidal
Anti-inflammatory Drugs (NSAIDs) used in
specific clinical condition.
3. Write short notes: (any 3 out of 4) (18)
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a. Low Molecular Weight (LMW) heparins.b. Mechanism of action, uses and adverse
effects of statins.
c. Therapeutic uses and adverse effects of
aspirin.
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d. Allopurinol.4. Answer only in 2-3 sentences: (any 5 out of 6)
(10)
a. Name any four biological agents used in
rheumatoid arthritis.
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b. Mention any two advantages of secondgeneration antihistaminics over first
generation.
c. Explain the pharmacological basis of
combination therapy of folic acid and vitamin
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B12 in megaloblastic anaemia.d. Write any two indications of using parenteral
iron therapy.
e. Give any two examples of drug combinations
to be avoided in hypertension.
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f. Mention any two uses of fibrinolytics.***
Document Outline
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