Date: 07-04-2016
PBJ 3025
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.
Section 1
Max Marks: 40
1. Multiple Choice Questions: (10)
a. Mydriasis produced by phenylephrine is due
Contraction of cireular muscle of iris (C) Bath
(D) None
b. Out of followings, which is the ideal
antihistaminiec for Truck driver with sneezing
Promethazine C) Diphehydramine (D)
Cetirizine
c. All are uricosuric drugs EXCEPT:
(A)Probenecid. (B)Sulfinpyrazone (C)
d. The mechanism of action of Disulfiram: (A)
Inhibits aleoho! dehydrogenese (B) Inhibits
aldehyde dehydrogenese (C) Increase
oxidation of aleghol. (D) Retard absorbtion of
e. Potassium channel opener that also acts by
nitric oxide release (A)Hydralazine
(B)Minoxidil (C)Diazoxide (D) Nicorandil
f. Spironolactone avoid in patient receiving: (A)
Hydrochlorothiazide (D) Verapamil
g. The following drugs act by inhibiting
H+K+ATPase enzyme in gastric parietal cells:
(A) Ranitidine (B) Rabeprazoile (C) Rioprostil
h. Which of the following statements is not
correct for local anesthetics?: (A) In a tissue
they exist either as an uncharged base or as
a cation (B) A charged cationic form
than an uncharged form (C) Lo?Dal
anesthetics are much less effective in
inflamed tissues (D) Low pH in inflamed
tissues decreases the dissociation of
nonionized molecules
i. Pharmacovigilance is to monitor: (A) Cost of
the drugs (B)Unauthorized drug companies
(C)Drug safety (D) Pharmacy students
Section 2
a. Treatment of severe migraine
b. Treatment of oraganophosphoronus
Poisoning
c. Treatment of open angle glaucoma.
a. Lignocaine:
b. Carbamazepine
c. plasma halflife
d. Proton Pump inhibitors
4. Write short notes on: (two out of three) (10)
a. ACE inhibitors
b. G-protein coupled receptors
c. Alpha blockers,
PBJ 3025
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
--- Content provided by FirstRanker.com ---
Instructions:1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.
--- Content provided by FirstRanker.com ---
5. Write legibly.Section 1
Max Marks: 40
1. Multiple Choice Questions: (10)
a. Mydriasis produced by phenylephrine is due
--- Content provided by FirstRanker.com ---
to:(A)Contraction of radial muscle of iris (B)Contraction of cireular muscle of iris (C) Bath
(D) None
b. Out of followings, which is the ideal
antihistaminiec for Truck driver with sneezing
--- Content provided by FirstRanker.com ---
and rhinorrhea: A) Pheniramine B)Promethazine C) Diphehydramine (D)
Cetirizine
c. All are uricosuric drugs EXCEPT:
(A)Probenecid. (B)Sulfinpyrazone (C)
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Colchicine (D)High dosages of Aspirin.d. The mechanism of action of Disulfiram: (A)
Inhibits aleoho! dehydrogenese (B) Inhibits
aldehyde dehydrogenese (C) Increase
oxidation of aleghol. (D) Retard absorbtion of
--- Content provided by FirstRanker.com ---
alcohol:. Coe. Potassium channel opener that also acts by
nitric oxide release (A)Hydralazine
(B)Minoxidil (C)Diazoxide (D) Nicorandil
f. Spironolactone avoid in patient receiving: (A)
--- Content provided by FirstRanker.com ---
Furosemide (B) Enalapril (C)Hydrochlorothiazide (D) Verapamil
g. The following drugs act by inhibiting
H+K+ATPase enzyme in gastric parietal cells:
(A) Ranitidine (B) Rabeprazoile (C) Rioprostil
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(D) Pirenzepineh. Which of the following statements is not
correct for local anesthetics?: (A) In a tissue
they exist either as an uncharged base or as
a cation (B) A charged cationic form
--- Content provided by FirstRanker.com ---
penetrates biologic membranes more readilythan an uncharged form (C) Lo?Dal
anesthetics are much less effective in
inflamed tissues (D) Low pH in inflamed
tissues decreases the dissociation of
--- Content provided by FirstRanker.com ---
nonionized molecules
i. Pharmacovigilance is to monitor: (A) Cost of
the drugs (B)Unauthorized drug companies
(C)Drug safety (D) Pharmacy students
Section 2
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2. Write short notes on: (two out of three) (10)a. Treatment of severe migraine
b. Treatment of oraganophosphoronus
Poisoning
c. Treatment of open angle glaucoma.
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3. Write briefly on (four out of five) (10)a. Lignocaine:
b. Carbamazepine
c. plasma halflife
d. Proton Pump inhibitors
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e. Potassium sparing diuretics.4. Write short notes on: (two out of three) (10)
a. ACE inhibitors
b. G-protein coupled receptors
c. Alpha blockers,
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